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question from a user

36 M - 4 weeks into treatment. 60MG test cyp injection Tuesdays and Fridays. Started w T level around 280 - all typical symptoms. Low energy, moodiness etc despite healthy lifestyle and diet. Question: not noticing any changes to date. Morning wood seems marginally improved but flaccid penis seems smaller and not achieving full erection/ premature ecaj during sex. Hormones leveling? Give this routine more runway to resolve the issues? Could it be an AI issue? Dosing issue?

AlphaMD's Answer

Check out this timeline we give to our patients:

- The Start, Weeks 1-4 - Many notice effects from the first few injections. During this time, more benefits will become apparent as the half-lives of previous doses build up in your system over time. It is important to give your body time to adjust to your initial dose.

- A Pause, Weeks 5-6 - During this time, many patients will experience a lull in benefits for a few days to a week. This is your body throwing a last "protest" about the new Testosterone before completely accepting it. This is normal, it will pass, and it does not mean you need to increase your dose.

- Evaluating, Weeks 7-8 - This is when your body has completely accepted your new Testosterone levels and is a good time to evaluate your treatment plan. Is all feeling well? Better than expected? Worse? We will send you a check-in survey around this time to touch base. If any changes need to be made, this is when it is fair to evaluate.

For you, I'd say it's fair to assume you may be coming up on the week 5-6 area. For most routines if you're just starting TRT for the first time we'd advise to wait until weeks 7 or 8 to look to make changes (normally). That's when everything is pretty stable & you can make fair evaluations.

I will say though, 120mg a week may be a few mg on the lower side for you, though you should notice some benefits. If things aren't improved by that 7 or 8 mark, we'd think that 140mg may be a bit better & worth a shot. It may also be worth taking a look at your Estrogen at that time & seeing if you should use an AI.

In the meantime, you could potentially swap to subq injections if you're not already to further limit Estrogen transfer, as they reduce the spikes which begin that reaction.

Finally it could be worth looking at libido vs just erectile function. If the desire is there & improved with TRT, then that's awesome since it's the harder part to pin down. However if erectile function is not, it doesn't hurt to add something like Cialis to the mix. Even men with everything else running great take it to enjoy themselves more. If your provider can go through CostPlusDrugs then you'd be able to get this incredibly cheap.

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