question from a user
At 1000 iu weekly, are there any long term side effects of the body no longer responding and producing LH?
AlphaMD's Answer
As answered in another question today, long term use of hCG does carry the risk of downregulation of the LH receptor. So we always recommend a "drug holiday" for those on hCG (3 months on/1 month off). The one month off "resets" the LH receptor. Otherwise, you will need a higher and higher dose over time to reach the same effect.
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