question from a user
AlphaMD's Answer
There is no specific level of estradiol that triggers initiation of an AI. Typically, they are prescribed only in the presence of estradiol associated symptoms. In our experience, many men will start to have symptoms at or above 40 pg/mL.
We personally take a stance that you shouldn't add an AI unless clear symptoms show up, as it's only ~25% of men who need it at our typical therapeutic doses. That said, we have no issues giving it ou... See Full Answer
In general we opt for a "lowest medication needed" approach, as most things in TRT have less benefits and higher side effects the higher you go in doses. For AIs, we find that most men do not need the... See Full Answer
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