Back to all Questions

question from a user

Can a small dose of trt (50 to 80 ml) weekly and small dose of enclomiphene (not clomid) be used? The reason for the enclomiphene is to keep a small number of my production going. Some people say it's useless the only reason would be to keep other hormones that the testosterone produce (pregnenolone, dhea etc)

AlphaMD's Answer

A dose of 50-80 mg (I'm assuming you meant that as opposed to mL) weekly is a dose that likely would typically get most men only to a level in the low 400s (a simple rule is that most men will convert 1mg of injected testosterone to between 4-6 ng/dL. So a man injecting 50-80 mg could expect anywhere from a level of 200 mg/dL to 480 ng/dL. These levels are below normal or low normal. Since testosterone injections suppress normal testosterone production, a dose this low would do nothing except shut you down and likely give you a T level at or below your baseline level anyways.

Adding enclomiphene, increases natural production of T by increasing both FSH and LH. There are no reliable studies that have paired TRT along with clomid or enclomiphene. But logically, adding one of these to TRT would at the very least help you maintain your fertility and the level of natural T you were to produce at your baseline.

Remember that most men have primary hypogonadism, which means the function of the testicles has failed. This means all the enclomiphene in the world won't raise your T levels by much. If enclomiphene does raise your T levels, then you likely suffer from secondary hypogonadism due to a pituitary disorder.

So, putting all that together: all you would do by taking a low dose of testosterone is shut down your natural production completely, and adding enclomiphene would restart your testicles to produce the same level they were producing before you started T. So you could basically add the 2 T levels (your natural production before TRT and your current T dose) together.

For example, say your natural T level before TRT was 250. You take 50 mg/wk of exogenous testosterone and convert it to 6 ng/dL = 300 ng/dL.

250 + 300 = 550 ng/dL.

While this level may be better than the 250 you were at before, it is likely not high enough to relieve the symptoms of hypogonadism.

Ready to get answers?
Ask your own question today.

Get $30 off your first month’s order

Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.

Legal Disclaimer

This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.