question from a user
Currently on TRT. Estradiol is 43.4 and DHEA 493.7. Are those levels concerning? I take 110 mg per week testosterone cypionate. No aromatase inhibitor.
AlphaMD's Answer
Those numbers don’t raise any red flags. Many men will start to experience symptoms of E2 at levels 40 and above, though plenty of men don’t. If you feel fine, then there is no need to add an AI.
DHEA is a precursor hormone and has no receptors in the body. It’s level is an indicator for the sex hormone cascade, which is essentially subverted on TRT, so it has little meaning in men on TRT.
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