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question from a user

Currently on trt last few months. 120 mg. HCT fine, estrogen fine, rbc, fine. All bloods perfect. I get weird hypersensitivity feelings, almost like prickling skin/ needles all over my arms, almost feels like my skin is sunburned. Hard to explain really. I get flushed feeling along with it sometimes, face gets red. I feel horrible actually. I’m wondering is this a common side effect? Could I be allergic to an ester or a carrier oil. I use grapeseed currently. The reaction isn’t at the injection site at all, or is it immediate. It’s a few days after injection I start getting these feelings. Also when I started I was at 480 total t, 17.2 direct

AlphaMD's Answer

The “prickly sunburned skin” sounds like paresthesia. This is typically due to inflammation, irritation, or compression of peripheral nerves. That is not a typical symptom of allergic reactions.

The “flushed” skin also is not typical of an allergy. Typically skin reactions in allergies result in hives, especially to injected medications. Flushed skin is often due to activation of the sympathetic nervous system, causing capillary dilation.

What you are describing may be due to a number of things. Electrolyte imbalance, B12 deficiency, dehydration, adrenaline release, anxiety, and some autoimmune issues. For this reason, I would recommend you follow up with your doctor for further testing.

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