Hey there, thanks for doing this. I have been on for about 18 months with minimal side effects then suddenly over new years I developed pancreatitis for the first time. Docs at the ER couldn't rule out TRT as a cause, but they didn't seem very knowledgeable. I'm waiting for an appointment with my endo, but that can isn't until the end of the month. Is it possible that its TRT related? Thanks in advance!

There are many potential causes for pancreatitis. The most common being excess alcohol use, and the second most common being due to gallstones. There is a rather long list of medications that can cause pancreatitis, though it should be said that it is a very, very rare complication of those medications. Corticosteroids is on the list of medications that can cause pancreatitis, but anabolic/androgenic steroids (like testosterone) are not.

Estrogen is listed as one of the potential medications that can cause pancreatitis. Considering this is a sex hormone similar to testosterone, it stands to reason that testosterone may have the potential to cause pancreatitis as well. Though if this is the case, you would be the first person for it to ever happen to.

There is a case study on one man who got pancreatitis from the use of trenbolone, though a case study is literally just one case. If testosterone is causing your pancreatitis, you will likely end up in a medical journal as a case study. Make sure you get some money from the journal if it is published!

Also, most cases of drug-induced pancreatitis occur very soon after starting the offending medication, typically after only a few doses. So the fact that you have been on TRT for 18 months rules that out as a possible cause in my mind.