question from a user
How can you make definitive inferences about T level changes based on two tests taken one year apart? (Knowing that there is notable methodological and biological variation in T test results.) How do you rule out placebo in treatment trials?
AlphaMD's Answer
Really the goal with treatment is to improve someone's condition, the goal is not to adjust someone's number (which is variable like you say).
If someone is feeling better after being properly Dx'd and treated at a therapeutic dose then everyone involved is quite happy.
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