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question from a user

How come RHR increases with TRT usage? My RHR used to be in low 50s and now is it is low 60 even with my cardio conditioning improving. Also, why does TRT make OSA worse?

AlphaMD's Answer

RHR increase on TRT - while this is not a common complaint, it is known to occur. While the phenomenon has not been evaluated extensively, a common theory is that increased viscosity (thickness) of the blood may be a cause. If you haven’t already, you should have your doctor check your hematocrit to see if this is true in your case. Another theory is that on TRT, your testicular function shuts down, and your body recognizes that. So it ramps up your adrenal gland production of testosterone (yes, your adrenal glands also produce testosterone, not just your testicles). Because the adrenal glands also produce adrenaline, the increased adrenal activity releases more adrenaline, raising your heart rate.

OSA worse on TRT - this is a much more widely known phenomenon, but still the jury is still out on exact reasons why it occurs. But interestingly, studies show that TRT negatively affects OSA in the beginning, and actually have a positive effect on OSA over time.

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