question from a user

How do you infer from those association analyses that it is indeed E2 and not too high testosterone that caused the anxiety?

AlphaMD's Answer

If you read the studies, you will see that they tested men with high T and high E, high T and normal E, normal T and high E, normal T and normal E, low T high E, and low T low E.

Based on their findings high E was what correlated to higher levels on anxiety scores.

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