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How does HCG affect total t, free t, and estrogen on top of current trt dose? If there is a large difference, would it be beneficial in some cases to lower trt dose so bloodwork doesn't get too out of line?

AlphaMD's Answer

HCG can effect this in some very specific cases. Usually it is if the HCG dose is moderate to high & the patient in question had a higher baseline Testosterone production. If you are maintaining more of a higher baseline Testosterone level, then that will be additive to the amounts given to the body via Testosterone injections. This could cause higher T levels & if that spike were to trigger a reaction from the body to cause additional aromatization then Estrogen would also increase.

However if the average very low Testosterone man were to start TRT & also HCG for baseline maintenance of the testicles for purely cosmetic reasons (meaning low dose HCG), the impact would be fairly minor & normally wouldn't cause much need to deviate from their TRT dosing.

So it would really depend on your starting values, your update from TRT & HCG, HCG dosing, and be very individual.

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