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How effective is tadalafil paired with TRT? Does it helps to reduce e2, and if so, do you recommend? And what daily dose to see synergy?Does it helps to reduce e2, and if so, do you recommend? And what daily dose to see synergy?

AlphaMD's Answer

It is common to combine the two when the initial symptoms of low Testosterone include low libido or ED. We tend to hold off on adding it right away to see if this can be resolved via Testosterone, otherwise it can be hard to draw conclusions from dosing.

We do not often see it as a way to reduce E2, as Testosterone dosage adjustment or an AI is a more consistent & direct method to handle this.

However, if this does not resolve or if a patient simply wants to add it for other reasons, we are more than happy to do so. It tends to help in the gym/vascularity as well as the bedroom. For that purpose we tend to suggest 5mg daily for a consistent approach, or 10mg as needed.

We work with CostPlusDrugs which allows us to charge a small fee of $30 to process an Rx with them, then a patient can obtain ~90 tablets for ~$15. In total, $45 for 90 tablets is significantly cheaper than even most ED focused treatment plans direct from pharmacies.

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