question from a user
How long after starting TRT does it take for estrogen to spike, if it’s going to? And what is the first protocol to stop it? Lowering the dose or adding an AI?
AlphaMD's Answer
Generally within the first 2 months you will notice an Estrogen issue or likely not have one. Everyone is a bit different.
The first step is modifying routine, then adding an AI, then lowering dose if that is the only side effect.
For us, as an example, we start people between 140mg-160mg a week divided twice weekly subcutaneously. Dividing the dose up & doing subcutaneous reduces T spikes & lowers the chance you will have an Estrogen issue at all. This tends to be the best method to not have to use an AI or lower the T dose.
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