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I am currently self administering TRT 125mg PW Sustanon to be precise (35yo Male, no known medical conditions or physical health issues besides MH & Low T symptoms) [self administrating as total Test came back low but just about 'within range' so docs NFA’d; But using total test, shbg & albumin I calculated my Free & Bioavailable test and both were below range, so after much thought & all symptoms pointing to low T I decided self admin would be the most cost effective and straight forward path to TRT] Anyway, apart from holding off testicular atrophy, what other benefits would HCG offer a patient who is currently experiencing no negative side effects at all; isn’t trying to sustain fertility (actually considering a vasectomy) and has no signs of e2 issues or other. [No AI or SERMs currently being used either] ? Since starting TRT have had a purely positive response i.e Increased Libido, improved mood & motivation, increased energy, improved mental health [less anxiety, MH issues & reduced symptoms of diagnosed personality disorder] etc Also, With regard to other health markers, what things should I be looking at on a blood test to ensure optimal health all around is sustained whilst self administering TRT. (Blood tests will be 4 x a Year via NHS(UK) and usually include as standard: Full Blood Count Urea & Electrolytes Liver/LFT Bone Profile Lipid profile (HDL/LDL/Triglycerides etc) Thyroid/TSH Testosterone SHBG Haemoglobin A1C level [although requested at previous test, Prolactin, Prostate, Estradiol, FSH & LH were not tested. I believe once I inform my GP that I’m self administering TRT they will be more inclined to include the ones missed out] So to sum up : a) what potential benefits or nevatives Could arise from adding HCG into TRT protocol [If added it would be purely to maintain fullness & size of Testicles] -&- b) what health markers on a blood test are imperative to keep an eye on and keep within range whilst undergoing TRT? Thanks :D

AlphaMD's Answer

There is very little issue adding HCG full time to a TRT regimen, though you want to be reasonable and only use 500-1000 units a week. Closer to 1500 units a week would be more for active child conception. The one thing to watch is that you may have slightly more Estrogen, though it's not often a lot or common. The usual reason to not add it just for the cosmetic aspect is the cost, as HCG can be expensive. If you have a ton of money then that may not matter. You would probably be fine (personal opinion).

For therapeutic ranges of TRT, those look to be perfectly good markers. Keep an eye on your RBC count over 6 months to a year, as that's one that can rise over time and may require blood donations. If your nipples get sensitive check out Estrogen more and either add an AI or change to more frequent subq injections. Testosterone is a very safe treatment, so if you're not having side effects and sticking to the same regimen, you may not need all of that testing unless you want it down the road.

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