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question from a user

I’m currently on enclo and got my first set of labs back this week (7 weeks in). Total T went up from 465 to 732 and E2 from 25 to 44. My Free T percentage dropped from 2.6% to 2.0% I’m concerned about this drop in Free T % and asked my provider for some options to help but no response as of yet. I’ve read this is common on enclo along with suppressed IGF-1 levels. Two questions: How would ya’ll address this situation with Free T % dropping? Also, for someone like me currently on enclo what would be the protocol to switch over and start actual TRT? Thanks!

AlphaMD's Answer

That can sadly be common along with the IGF-1 issue, as you say, with Enclomiphene. I can see the logic of you being on the line between primary/secondary or relative at 465 which may have made Enclomiphene sound like a potential treatment. Normally we would still prefer injectable TRT at this level, but I wouldn't say it was the wrong call to start.

In this situation, we would probably suggest exactly that - to give the injectable form a try & see how that improves your free T, along with how you personally feel on higher IGF-1.

For switching protocols, we'd advise to work with someone who will take your pre-treatment lab results and not force you to come off of treatment to prove eligibility. If they ask you to do so, avoid them. Past that, you'd want to make sure you start the process while you have at least 4 weeks of current treatment available if possible just incase there is a delay in medications shipping out from pharmacies. There's no difficulty switching between treatments after those two concerns, we've had many men do it.

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