question from a user
I’m having a hard time controlling my blood pressure. Since starting T my diet is clean and I’m in better shape. Is there anything you recommend?
AlphaMD's Answer
Most men do not have problems with blood pressure while on TRT, though in a few cases, they can. Overall, it has been proven with evidence that testosterone is cardioprotective, and actually lowers blood pressure.
On the other hand, there is evidence that testosterone can increase the vasoconstrictive aspects of the renin angiotensin aldosterone system. Testosterone can upregulate angiotensinogen gene expression, renin activity and AT1R expression. When these are increased, you will have more vasoconstriction as well as water and salt absorption that increases fluid volume in the body and will have a increase in blood pressure.
If you struggle with high BP on TRT, be sure to ensure you are not running supraphysiological testosterone levels chronically (true TRT), reduce salt intake, exercise regularly, reduce excessive alcohol intake, get quality sleep hygiene, and reduce stress.
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