question from a user
I'm on a 2000 IU, 3x a week (6k...) dosage of hcg after having done trt for 2 years. The hcg does totally make me feel better, but my dosage feels a bit wack from my urologist, no? I'm attempting to preserve fertility and the wife and I are actively trying. My test cyp is 140mg split 2x a week and it has me hovering at 900 test, but my estrogen has and continues to be the problem. Uro wants me on 1mg Anastrazole 2x a week and I think I've crashed my estrogen, again. E2 dialing in has been way more difficult than test, by far. I'm considering not even doing ANA ever again and dealing with high e2. Whats your guys non medical advice of this protocol, or if that question is too controversial, what protocols do you often see for duotherapy of hcg & trt?
AlphaMD's Answer
That is a relatively high dose of HCG, though if you are trying for active conception, that could be fine until it occurs. After that, it may be wise to lower it down. It is likely causing an issue with your E as HCG can have a larger impact on this than traditional Testosterone injections.
For reference, we typically put men on 1500 units a week for active conception at least 3 months before the target conception time period. If you are at that dosing & trying, yet getting no results, it may be worth it to look into checking your sperm count with a fertility specialist & ensure that you're not the issue in the equation. Some times a women may have lower fertility & it may have nothing to do with you at all. If a man has issues with conception while on that level of HCG, we'd probably momentarily cycle him off Testosterone & keep him on HCG monotherapy (only until conception) to try and provide the best odds. This is a large generalization though, and is very patient to patient.In an ideal world, you would obtain conception & then if fertility is important to you in the short term (next 12 months) you could drop down to 500 units week for pure maintenance. That would likely help with the Estrogen issues & you could drop down the AI use.
For AI use, 2mg a week is the highest we will ever go. 0.25mg to 1mg weekly is far more common & usually does that job. In cases that it doesn't, there's usually something else driving E up (potentially so much HCG). The best way to know for sure if your AI is dosed correctly would be to get more testing done. Test your levels a few times at that dose, make sure it's not flattened, and if it is lower to 1.5mg weekly, then repeat. Ideally, there is a perfect sweet spot for you where you are not low or high, and have no negatives from either, but it can sometimes take work to get there.
Ready to get answers?
Ask your own question today.
Get $30 off your first month’s order
Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.
Legal Disclaimer
This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.