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I’ve been thinking about how to have the conversation with my primary care doctor. I had a testicular torsion during my teenage years and would bet that definitely had an effect on my levels. Currently taking Buproprion, Stratera, Hydroxyzine, and Quetiapine daily. I asked my psychiatrist this week if starting TRT would have any interactions with my meds and they said no which was good to know. I have struggled with libido for most of life and it has gotten worse with the meds. I got my levels checked last year and had a Free Testosterone level of 111.7 pg/mL and a Testosterone level of 718 ng/dL so my primary care physician said my levels were fine. Really thinking I want to look deeper into trying to start T though. Any thoughts on starting it with the amount of Meds I am along with being in a Biologic for Crohn’s? I get super fatigued when I am due for my infusion of Entyvio and wonder if T would help anywhere. Besides the physical help with the gym and gymnastics, I have trouble keeping muscle/strength even as my reps/weight increases. Not seeing a ton of physical difference even though i eat relatively healthy and try to get enough protein because of the crohn’s.

AlphaMD's Answer

It is true that TRT would not have any interaction with your current medications.

The T levels you listed would be considered normal. Would even higher levels help with the medication induced drop in libido?Possibly, though the medications you take affect a different system that affects libido; serotonin, dopamine, and norepinephrine. Testosterone does not play any significant role in those neurotransmitters.It is common for low testosterone to cause or worsen anxiety and depression, but with your labs being what they are, I cannot say for certain that you would attain any benefit.Of course higher androgens would assist with your goals regarding your fitness.

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