question from a user
I was recommended by a clinic to take Anastrozole starting week 2. I started week 3 and have taken it for 4 weeks. It could have been the initial boost of the injections I was filling, but feel like I dont have that natural energy feeling and joy I had initially. I’ve read that it isn’t really necessary unless you get side effects from the presence of excess estrogen. Could my reemergence of fatigue be due to the Anastrozole? What are your thoughts?
AlphaMD's Answer
During weeks 1-4 most men find increasing benefits week over week.
Then during weeks 5-6 some of that shut down does occur, but your body also throws a tantrum about the outside Testosterone. The reason isn't clearly understood, as they are indeed the same substances as your normal hormones, but it does happen most time. We advise men during this time to expect a drop in benefits for a few days to a week, then they should return.
Finally during weeks 7-8 most things should be stable & it is a good time to evaluate if the dose is right for you.
While we have the opinion that most men don't need an AI at therapeutic doses, the timing here is likely for the reasons above & you should probably ride it out until that week 7-8 mark and then make a choice to modify your program or not.
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