question from a user
If someone was at 2000ng/dl and one person required 200mg/week and the other 400/week, would the person on twice the dose incur twice the amount of health impact?
AlphaMD's Answer
Replying to this as a hypothetical scenario, as we do not treat individuals to these levels: Yes we would expect more health issues for the patient taking the higher dose there. Would it be double? Less than double? More than double? Hard to say haha but we would agree with you mostly.
We'd be more interested in where they got their testing done, most places cap out at 1500 & don't bother.
But essentially, once all the androgen receptors are saturated, then there is nothing left for the testosterone to attach to. This means it either is aromatized to estrogen, converted to DHT, or just metabolized away before it gets the ability to attach to receptors, and is wasted. Both E2 and DHT are typically where the side effects of TRT come from.
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