Back to all Questions

question from a user

If someone were to experience a drastic reduction in free testosterone levels (over 40%) with mild increase in SHBG and E2 on 3x weekly injections at a therapeutic dose, what protocol changes would you recommend (in the absence of ancillaries)?

AlphaMD's Answer

I think this was posted in our other thread too, so I'll copy the reply here for others -

Would this be out of nowhere or just a few weeks into treatment/dose adjustment? If we're counting AIs as ancillaries in this then the 3x weekly is already a good step, but we would go further and ask for those to be subq instead of IM. Subq has been shown to absorb much slower & create less T spikes in the body which might prompt extra E transfer or SHBG production from the liver.

Ready to get answers?
Ask your own question today.

Get $30 off your first month’s order

Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.

Legal Disclaimer

This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.