Is it possible for enclomiphene to “kickstart”Testosterone production? Example, 46yo male, 5’10 167lbs works out, eats good, sleep is pretty good, low stress, no known medical problems or reason to have low range testosterone 320t/6f. I took a 7 day round of enclomiphene 6.25 and it bumped it up in the 700s immediately. I don’t like medication and prefer to stay natural as long as possible and I don’t mind fighting for it. I’m working with a NP to find the root cause by in-depth testing and yet to find anything?

In 16 years of practicing medicine, I have never seen anything “kickstart” testosterone production.

The analogy I have used in this case is to think of your testicles as a car engine which is not functioning very well. You can add octane booster, and get some increased performance out of that, but as soon as you stop adding the octane booster, the engine starts to run poorly again.

Hypogonadism is becoming very prevalent in all age groups. The fact that it is a universal phenomenon (all men have 33% less testosterone than their fathers did at the same age), suggests that it is an environmental factor. Could it be that all humans now have on average almost a pound of micro plastics embedded inside us, each releasing hormone disruptors? Could it be air pollution (see link below I couldn’t create hyperlink). Could it be birth control and other industrial chemicals in our water supply? Could it be the exposure to hormones in our meat supply? Or, more likely, is it all of these things combined?

Your NP won’t likely find a cause, because there are no labs for these things, at least none outside of a clinical trial setting.

https://www.sciencedirect.com/science/article/abs/pii/S0013935122004443#:~:text=An%20increase%20of%2010%20μg,within%20lag%200–30%20days.