question from a user
Is there any real difference between SubQ and IM injections? Starting TRT in a few weeks and have a pretty strong phobia of needles
AlphaMD's Answer
For overall average testosterone throughout the week there is not much change. However subq is better at managing Estrogen symptoms because it absorbs slower (releases slower) than IM. Because of this your T spikes are lower and your valleys higher, which trigger less responses in your body to produce Estrogen/transfer from Testosterone.
Subcutaneous injections are much more common and recommended in the last 5-10 years because of this and little downside. Most people tolerate the smaller needles better as well, it just takes slightly longer to inject.
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