question from a user
Looking into stopping TRT for a while and starting enclomiphene (for fertility). I've read that clomiphene can get your test numbers into the reference range but some people say it feels horrible compared to TRT and the numbers don't reflect the symptoms. The same thing seems to be true with a subset of TRT itself. (ie., you can get your numbers back into the reference range but still feel bad and have low libido). In both scenarios is there any solution?
AlphaMD's Answer
The reason it doesn't feel as good as normal TRT is that Clomid/Enclomiphene suppress IGF-1, which is what builds/maintains muscle & provides many of the benefits many people expect on TRT. On someone with relative hypogonadism (higher baseline Testosterone) this is generally fine & more of a boost than anything as they have so much to work with. On those with primary or secondary it can feel bad. So on paper your T may be up but your IGF-1 won't be.
We'd suggest using HCG 1500 units a week, 75% of men are able to stay on TRT while taking that dose & still have a child rather than cycling off. It doesn't really hurt to try first before coming off & dealing with low T symptoms again.
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