question from a user
Many people are talking about using hcg instead of clomid, but hgc is simply an analogue of LH. when it comes to fertility explicitly you need both gonadatropins right? Clomid mediates it's effects through both LH and FSH. so a combination should be best if you are trying to get the Mrs pregnant, as hgc will act as Lh and clomid will stimulate some FSH. I think bothe should be used while trying to get herself pregnant... I know it's anecdotal, but that worked for me
AlphaMD's Answer
You are right in that Clomid provides better fertility than hCG because it also increases FSH, which we now know matters less for sperm count, and more for sperm quality (motility and morphology).
Newer science shows that the most important aspect for sperm count is intratesticular testosterone levels. Both hCG and Clomid accomplish this equally.
So sperm counts should be similar on both Clomid and hCG, but sperm on Clomid is of better quality.
The primary reason hCG is chosen is usually due to the different side effect profiles. HCG has very few side effects and is universally easily tolerated. Clomid has many side effects, and few can take it for long before needing to stop.
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