question from a user

My girlfriend has PCOS and has been spending years trying to figure out how to treat it. Doctors are zero help when she tries to see one, and she has seen a LOT. Would someone with PCOS benefit from hormone therapy at all??

AlphaMD's Answer


Without knowing the specifics of her particular case, I can only say that”maybe”.

So, ovaries actually produce testosterone first, then convert the testosterone into estrogen through aromatase. PCOS disrupts this, typically causing an excess of androgens and diminished aromatase activity.

Adding hormones to help regulate the female cycle and assisting with ovulation can help in the treatment. So yes, hormones do have a place in PCOS treatment.

Weight loss and regulating insulin and glucose levels help a lot in PCOS. In fact, GLP-1 agonists (ie. Ozempic) are now approved for PCOS.

PCOS treatment is a long road, but it can be managed, and even cured with the right pharmacologic regimen combined with lifestyle changes.

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