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My last test @ 8 weeks showed 953 test with 50 estrogen at my trough. I inject 3x times per week 50mg per injection totaling 150mg test c per week. Unfortunately my current provider only provided me with those metrics and nothing else. How do I reduce anxiety while on trt? I’ve been on for about 3 months now and my anxiety post injection is high for a few days. Should I lower dose? Increase injection frequency? Should I test for something else?

AlphaMD's Answer

Again, we are not able to diagnose anything via Reddit, but just a few thoughts.

Many men experience E2 symptoms at levels that exceed 40. At a level of 50, I would say that that level has certainly caused symptoms including anxiety in many men.

Another thought is that thyroid issues cause many symptoms that are similar to those of hypogonadism, and anxiety/depression are common. I would say looking into that would be wise.

You certainly have some wiggle room if you wanted to lower your dose. Increased frequency would also likely help lower your E2.

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