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question from a user

My problem is that my low shbg is causing me to have a low libido and erectile dysfunction. Do you have a solution when this happens? I’m already microdosing, but some ”experts” says that it’s better with infrequent big doses to drive up the shbg.

AlphaMD's Answer

SHBG can be tricky, but traditionally high boluses of a sex hormone like testosterone will trigger the liver to make more SHBG. Doing daily "microdoses" basically attempts to slip in the testosterone "under-the-radar". If the dose is low enough, it does not trip the alarm and your liver will not produce more SHBG. So yes, higher doses will "trip the alarm" and make your liver produce more SHBG.

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