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Psa and trt- what are your thoughts?

AlphaMD's Answer

We follow the recommendations regarding this and have all men age 55 and older have a PSA before starting TRT.

TRT raises DHT levels, so it is expected that PSA levels will increase. Studies have shown that there are raises of 0.30 ng/mL/y in serum PSA, with older men experiencing a greater increase of 0.43 ng/mL/y in men on exogenous testosterone.

Any high risk patients should have PSA tested at baseline, again 6 months after starting TRT, and then semiannually from then on.

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