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Question regarding HCG and HTN: I had a weird experience on 200units of HCG. I was prescribed 500 units three times a week but did a test dose of 200units. A few hours after injecting, I felt a sharp pain on the left side of my head- almost like a vasospasm. Right after that I could feel my blood pressure spiking. I measured it and it was around 170 SBP. I am normally high 120s. That was accompanied by a feeling of tingling (and I think numbness) on the tight side of my face and arm. Went to the ER and troponin and EKG were negative. After a few hours my BP went down to normal. Could this have been due to a spoke in estradiol, or a blood clot? My Urologist, who prescribes TRT, said he'd never seen this happen before and he recommended a test dose in his office, in case we needed to take me to the ER again. What are your thoughts please? I'd appreciate any feedback!

AlphaMD's Answer

First of all this sounds very scary and I am glad to hear that you have no long-term affect from this incident. I'm also glad to hear that you were cleared in the ER.

hCG levels can trigger a surge of aldosterone production in the adrenal gland, which can increase blood pressure. I have not seen this happen and is not common. You may be very sensitive to this, or it could be something that happened which was transient and not detectable after the fact.

If it is something you are comfortable doing you could try it in the office again where at least it's being monitored and more of a controlled environment. I would recommend you only do something you are comfortable doing, and would do a much lower amount if you decide to try again.

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