question from a user
This is two years of 6 month interval tests including FSH and LH Here’s a summary of my Total Testosterone and Free Testosterone numbers over time: Total Testosterone (nmol/L, Range: 8.4 - 28.8): • 27-Sep-2024: 13.0 nmol/L • 4-Apr-2024: 13.0 nmol/L • 22-Feb-2024: 8.0 nmol/L (weird test after two weeks of a medication) • 4-Oct-2023: 12.2 nmol/L • 5-Apr-2023: 12.4 nmol/L • 8-Dec-2022: 12.9 nmol/L Free Testosterone (pmol/L, Range: 196-636): • 7-Sep-2024: 240 pmol/L • 4-Apr-2024: 258 pmol/L • 22-Feb-2024: 124 pmol/L (weird test after two weeks of a medication) • 4-Oct-2023: 244 pmol/L • 5-Apr-2023: 260 pmol/L • 8-Dec-2022: 267 pmol/L . Here are my FSH and LH results over time: FSH (IU/L, Range: 1.0 - 8.0): • 27-Sep-2024: 4.0 • 22-Feb-2024: 4.4 • 4-Oct-2023: 5.1 • 5-Apr-2023: 5.0 LH (IU/L, Range: 1.0 - 7.0): • 27-Sep-2024: 2.0 • 22-Feb-2024: 1.5 • 4-Oct-2023: 2.4 • 5-Apr-2023: 2.4
AlphaMD's Answer
Your LH levels are lower than expected for your T levels for true isolated primary hypogonadism. You may have some mixed hypogonadism (both testicular and pituitary dysfunction). Based on this, I would expect you to have some moderate improvement with hCG monotherapy though you would likely need to switch to TRT within a relatively short period (less than 2 years) as in most cases of mixed hypogonadism, the decline worsens with time.
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