The best case & results we've seen for it's use has been for men who have higher base Testosterone levels, aka relative hypogonadism TRT candidates. Since it is another medication which boosts your production of Testosterone rather than just adding to it the limiting factor to what it can do is generally a person's production capabilities. The lower someone's natural production the less of an increase you can expect most of the time. "20% more of nothing is still nothing".

The main downside to Enclomiphene or Clomid would be the impact it has on IGF-1, lowering it. Since IGF-1 is responsible for many of the muscular/fitness improvements men expect on TRT or one of the reasons many men look to start TRT this can be a bit confusing for them. The Testosterone on paper goes up but the "gains" don't improve as much as expected.

In the absence of traditional TRT we would still prefer Enclomiphene to nothing for someone with primary/secondary hypogonadism & very low Testosterone production, but if we can convince someone to go with injections instead then we would. That and Enclomiphene can cost more depending on the dose than Testosterone, which is weird to us but we don't own the pharmacies.