question from a user
What are the earliest signs that you might need to use an AI? What’s the lowest effective dose of arimadex/anastrazole?
AlphaMD's Answer
Sensitive nipples is the number one easy to spot symptom for a man. There's other things like noticing you cry when watching movies that you typically wouldn't feel emotions over, but that's a lot more subjective. Men can usually tell when their nipples are suddenly sensitive though.
A lot of men at therapeutic non-bodybuilder doses don't end up needing AIs & we typically don't start with them without previous history or reasons to do so. That's because if they don't have high transference you might bottom out their natural Estrogen, and some Estrogen is important to have as well.
A dose as low as 0.25mg once weekly is something we would consider & see how it goes, then go up to 0.5mg once weekly/0.25mg twice weekly with injections. You can go up to 1mg weekly but too much higher than that & you may want to look at increasing frequency or switching to subq rather than just pumping more meds.
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