question from a user
What's the indication for Subcutaneous vs IM administration? Personal preference? Skill?
AlphaMD's Answer
In general Subq is better for TRT when given both options because the absorption is slower & leads to a more even level overall, so there are less spikes which might cause additional Estrogen transfer. However not all men can handle Subq without local area irritation, and in those cases or when higher volumes are involved IM can be better. We've found most men stick with whatever they try first & have a strong opinion about switching, so we try to start them on Subq.
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