question from a user
What your thoughts are on men with Crohn's disease taking testosterone I know my levels are low from years of severe malnutrition and Prednisone use in between the biologics I failed when trying to get my disease under control I've now gotten symptoms under control live a semi normal life but I can tell something is still missing I've been over 200 plus my whole life all the back to 6th grade and muscular but not now I'm lucky to get up to 175 with very little muscular development low sex drive well basically none and extreme fatigue do you think my Dr would actually consider trt for me even if my t is extremely low oh and I'm 26 BTW
AlphaMD's Answer
Testosterone is actually an approved treatment for Crohn's DiseaseTestosterone therapy in men with Crohn's disease improves the clinical course of the disease: data from long-term observational registry studyAdministration of testosterone to elderly hypogonadal men with Crohn's disease improves their Crohn's Disease Activity Index: a pilot studyDo Androgens Modulate the Pathophysiological Pathways of Inflammation? Appraising the Contemporary Evidence
We have known for over a decade that TRT reduces inflammatory proteins like CRP, TNF-α, IL-1β, and IL-6. All the available data on TRT and Crohn's Disease is very positive, with several cases put into remission.Your frequent use of corticosteroids will certainly increase the likelihood that you are hypogonadal.
Crohn's really sucks. Im sorry you have had to deal with that. But show your doctor these studies, if he isnt already aware (many aren't as this is new science). I would be surprised if s/he didn't start you on TRT based on just what you have mentioned here.
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