question from a user
When you say there isn't much point increasing test but lowering igf-1 in a low testosterone male, is that from a physical or mental point of view as well? Personally I'm 100 total testosterone at 33yo and tried enclo for 3 months which boosted it to 375 then 525 with a little anastrozole (still 47 estradiol after) I felt like I was getting both mental benefits and a little bit stronger. Waiting on results from an MRI before I hop back on Enclo at the moment.
AlphaMD's Answer
IGF-1 has no mental benefit. It does have a very outsized benefit in regard to strength and muscle gain. Even more so than testosterone in fact. So that statement was just referring to the fact that with TRT you get both the mental and physical benefits, whereas with enclomiphene, you primarily get the mental benefits with a blunted physical response.
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