question from a user
Why did I get brain fog from TRT (Androgel)? Could not think anymore. Any ideas why that could be?
AlphaMD's Answer
The thought regarding this is that use of exogenous TRT shuts down all upstream steps in the hormone cascade. Some of these hormones have effects on the brain, in particular pregnenolone. As you can see in the cascade, adding pregnenolone essentially helps replenish what would be lacking once you start TRT. Pregnenolone is cheap and over the counter. We have seen many men have improvements with brain fog just by adding in this cheap supplement to their TRT regimen.
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