Aromatase Inhibitors - Reddit AMA #1, Part 1
People are asking...
What is the best way to prevent aromatizing too much? Does it have to be meds or are there legitimate supplements, diet etc...
Aromatase is primarily found in adipose (fat) tissue. So weight loss is the most important way to naturally reduce aromatization. You can also eat foods that are high in natural aromatase inhibitors l... See Full Answer
Pls elaborate on Efficacy of puberty gyno management with Raloxifene? If someone is know aromatizer - what is most intensive AI protocol?...
Use of raloxifene or tamoxifen for gynecomastia. It works in every case I have seen, but to varying degrees. Obviously, the more pronounced the gyno, the longer it will take, and the less likely it w... See Full Answer
What would the symptoms of the initial aromatization (if that’s a word?...
Being overly emotional, fluid retention/bloating, acne, and nipple sensitivity/breast swelling. Other symptoms can include low libido and weak erections (which can occur with low estrogen as well).... See Full Answer
Estrogen reducers are quite expensive. Would Arimistane ( Androst-3,5-diene-7,17-dione )be a suitable alternative? And if so at what approximate dosag...
Arimistane should not be considered an aromatase inhibitor in the traditional sense. Unlike medications like anastrozole or letrozole, which block aromatase, but releases it several days later, Arimis... See Full Answer
I just started TRT and was put on 180 mg test cypionate and anastrozole. Reddit hates AI but my physician put me on it. The huge amount of people sayi...
Never let the people on the internet get between you and a physician you trust. That being said, here are some general thoughts… The primary idea in any field of medicine is that “less is more”. By th... See Full Answer
What AI do you prefer? Why? What's the average dose, frequency?...
Anastrozole is preferred primarily because it can be taken less frequently than others, and it is also the most widely used and widely studied, meaning it is the easiest to source from pharmacies. Rel... See Full Answer
What are options for AI if allergic to arimidex?...
If allergic to that (Anastrozole) then daily Exemestane can be an alternative. There are others as well, though some have more side effects. I would also trying splitting your dose up more, switching ... See Full Answer
What are your thoughts on using Primobolan as an AI instead of Arimidex or Aromasin? I have been told that there have been recent studies which shows ...
In general, low doses of Primobolan have been used as a part of TRT protocols in countries where it is legal. It does help manage estradiol levels and is known to free up more free testosterone from S... See Full Answer
How do I deal with 0 estrogen conversion? I take 200mg no ai weekly and my levels are ideal. but I get hot flashes and horrible low estrogen symptoms....
If you have low natural aromatase levels, and aren't looking to take more injections, you can do essentially the opposite of what we would normally suggest for Estrogen management. You can increase ar... See Full Answer
What can you do for someone high estrogen and can't take ai ?...
What would be the reasons that you can't take AIs? It would probably affect the answer, as there's many reasons people don't want to take them. In general, we don't actually give out AIs all that oft... See Full Answer
Have a question? Ask us.
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Excerpt from our first Reddit AMA podcast video: What are aromatase inhibitors? Who should use them and why? Are they the same for everyone?
Transcript
This editable transcript was computer generated and might contain errors. People can also change the text after it was created.
Have a question? Ask us.
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
What's your take on aromatase inhibitors?
Brian Mckinley: And so there's a couple of things about that. So what it, what is that right? What are a eyes? When you all go on to your tea, you're injecting or adding outside testosterone to your body. Your body likes to maintain a stable environment between testosterone estrogen. It doesn't like when they change. And so when you add more testosterone, your body tries to change that ratio back to the way it was take some of that testosterone turns it into estrogen. AI is essentially tell your body. Do not do that. And in a lot of cases, that's what a lot of people do want, because they're looking to get more testosterone, not necessarily more estrogen, And so there's a lot of opinions on this which is either AI's do nothing, AI's are good guys, or AI's are bad.
Brian Mckinley: And so what's the opinion of professionals and people who would prescribe it? Well, the answer is that like all those are correct. Those are all correct answers.
Brian Mckinley: And when it comes down to is personal need because every single person is different, right? So some people, maybe they need more estrogen in their life, where? Okay, they add some testosterone extra. Estrogen is good for them. It turns out, they don't get any of the negative side effects from it, because what it also does is it can improve your mood. If it's the right amount it can help a lot with libido. And estrogen is also responsible for maintaining a lot of other bodily functions that can also help with like weight loss, things like that. And so having a healthy balance of that is quite good and so some people may not need it at all, and it may be beneficial to not prescribe it. Whereas on the opposite side of that.
Brian Mckinley: Some people don't need it and then do get prescribed. It and what it does is just bottom out there estrogen. So for those people, that's totally not good. Now all of a sudden, you know, they're having libido issues. They can't drop weight. Their feelings, get all mixed up and the third and final one. Someone has a lot of side effects. You know, we have we have patients who, you know, after they inject same day they get, you know, essentially sensitive nipples. Like they have the side effects and the absolutely need it. They take the pill. Those sensitive nipple feelings, go away. There's no concern for any gyno or anything like that. And so what it really is is you need your provider To take a look at that with you us as a TRT provider, our main approach is to not prescribe it, unless people need it.
Brian Mckinley: Kind of see how you go because again, the thing about bottoming out that estrogen can actually make you feel really bad. And you're not, you're not going to know until you see someone. How they respond to treatment. So, like, one size doesn't fit all on this category. And so for us, it's good. If it's good for you, it's bad. Bad for you. You need someone to look at it AIs are useful. They do what they do, but they're completely separate for everyone. That's our take on it.
People are asking...
What is the best way to prevent aromatizing too much? Does it have to be meds or are there legitimate supplements, diet etc...
Aromatase is primarily found in adipose (fat) tissue. So weight loss is the most important way to naturally reduce aromatization. You can also eat foods that are high in natural aromatase inhibitors l... See Full Answer
Pls elaborate on Efficacy of puberty gyno management with Raloxifene? If someone is know aromatizer - what is most intensive AI protocol?...
Use of raloxifene or tamoxifen for gynecomastia. It works in every case I have seen, but to varying degrees. Obviously, the more pronounced the gyno, the longer it will take, and the less likely it w... See Full Answer
What would the symptoms of the initial aromatization (if that’s a word?...
Being overly emotional, fluid retention/bloating, acne, and nipple sensitivity/breast swelling. Other symptoms can include low libido and weak erections (which can occur with low estrogen as well).... See Full Answer
Estrogen reducers are quite expensive. Would Arimistane ( Androst-3,5-diene-7,17-dione )be a suitable alternative? And if so at what approximate dosag...
Arimistane should not be considered an aromatase inhibitor in the traditional sense. Unlike medications like anastrozole or letrozole, which block aromatase, but releases it several days later, Arimis... See Full Answer
I just started TRT and was put on 180 mg test cypionate and anastrozole. Reddit hates AI but my physician put me on it. The huge amount of people sayi...
Never let the people on the internet get between you and a physician you trust. That being said, here are some general thoughts… The primary idea in any field of medicine is that “less is more”. By th... See Full Answer
What AI do you prefer? Why? What's the average dose, frequency?...
Anastrozole is preferred primarily because it can be taken less frequently than others, and it is also the most widely used and widely studied, meaning it is the easiest to source from pharmacies. Rel... See Full Answer
What are options for AI if allergic to arimidex?...
If allergic to that (Anastrozole) then daily Exemestane can be an alternative. There are others as well, though some have more side effects. I would also trying splitting your dose up more, switching ... See Full Answer
What are your thoughts on using Primobolan as an AI instead of Arimidex or Aromasin? I have been told that there have been recent studies which shows ...
In general, low doses of Primobolan have been used as a part of TRT protocols in countries where it is legal. It does help manage estradiol levels and is known to free up more free testosterone from S... See Full Answer
How do I deal with 0 estrogen conversion? I take 200mg no ai weekly and my levels are ideal. but I get hot flashes and horrible low estrogen symptoms....
If you have low natural aromatase levels, and aren't looking to take more injections, you can do essentially the opposite of what we would normally suggest for Estrogen management. You can increase ar... See Full Answer
What can you do for someone high estrogen and can't take ai ?...
What would be the reasons that you can't take AIs? It would probably affect the answer, as there's many reasons people don't want to take them. In general, we don't actually give out AIs all that oft... See Full Answer
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