How to Mix HCG: A Step-by-Step Guide

If you’ve been prescribed HCG (human chorionic gonadotropin) as part of your hormone therapy, understanding how to properly mix and store it is essential for safe and effective use. HCG is often used in conjunction with testosterone replacement therapy (TRT) and other hormonal treatments to support fertility, maintain testicular function, or balance hormones in both men and women.This guide will walk you through how to mix HCG at home, what materials you’ll need, and important safety considerations to keep in mind.

What You’ll Need to Mix HCG

Before starting, gather all the necessary supplies. These are typically provided by your pharmacy, but always check your prescription and instructions carefully:

• HCG powder (lyophilized form) – comes in a vial
• Bacteriostatic water – used to reconstitute (mix) the HCG
• Mixing syringe – usually a large syringe for transferring the water
• Alcohol swabs – for sterilizing vial tops
• Storage vial – often the original vial is used, but a separate sterile vial may be provided
• Refrigerator – for storing the mixed solution

Step-by-Step Instructions: How to Mix HCG

Step 1: Wash Your Hands

Start by thoroughly washing your hands with soap and warm water. Clean hands help prevent contamination.

Step 2: Prep the Vials

Use alcohol swabs to wipe the tops of both the HCG powder vial and the bacteriostatic water vial.

Step 3: Draw the Bacteriostatic Water

Using your mixing syringe, draw the prescribed amount of bacteriostatic water. Common instructions involve mixing 1 mL, 2 mL, or more, depending on the dosage prescribed by your provider.

Step 4: Add Water to the HCG Powder

Slowly inject the water into the vial containing the HCG powder. Aim the stream of water against the side of the vial to avoid foaming. Do not shake the vial; instead, gently swirl it until the powder is fully dissolved.

Step 5: Store the Solution

Once mixed, store the HCG vial in the refrigerator (36°F to 46°F or 2°C to 8°C). The solution is usually good for up to 28–30 days, but follow the storage instructions provided by your healthcare provider or pharmacy.

Common Questions About Mixing HCG

Can I mix HCG with saline instead of bacteriostatic water?

No. Bacteriostatic water contains a preservative (benzyl alcohol) that prevents bacterial growth, making it safer for multi-dose use. Always follow your provider’s instructions and use the correct diluent.

What happens if I shake the vial?

Shaking HCG can denature the delicate hormone, rendering it less effective. Always gently roll or swirl the vial instead.

Is it okay if there are bubbles in the vial after mixing?

Small bubbles may appear but will typically settle. You can also gently tap the vial to help release any trapped air.

Why Patients Use HCG with TRT

In men, HCG is often prescribed alongside TRT to help maintain natural testosterone production, preserve fertility, and prevent testicular shrinkage. For women, HCG may support ovulation and hormonal balance depending on the treatment goals.Because HCG mimics the body’s natural LH (luteinizing hormone), it plays an important role in reproductive and hormonal health.

Final Thoughts

Learning how to mix HCG properly is an important part of taking control of your hormone therapy. It may seem intimidating at first, but with proper guidance and a little practice, the process becomes second nature.At AlphaMD, we offer guided support throughout your treatment journey. Whether you’re starting TRT or using HCG for other hormonal needs, our licensed providers ensure that you receive expert care with medications delivered straight to your door.