Starting TRT: What to and not to be concerned about with Testosterone

Author: Alpha MD

What do people worry about when starting TRT? What isn't an actual concern? What should you know?

As more men consider testosterone replacement therapy (TRT) to address the symptoms of low testosterone, questions about its safety and potential side effects frequently arise. This AlphaMD YouTube video tackled the most common concerns about TRT, offering insights backed by the latest research. Here’s a summary of the key points to help you make an informed decision.


1. Prostate Cancer Concerns

A long-standing myth associates TRT with an increased risk of prostate cancer. This belief stemmed from an outdated study that has since been debunked.

  • What the Research Says:

    • Recent, high-quality studies have shown that TRT

      does not increase the risk of prostate cancer

      .

    • The American Urological Association has updated its guidelines, allowing even men with a history of treated prostate cancer to use TRT safely.

  • What About Existing Prostate Cancer?

    • The relationship between TRT and existing prostate cancer is still debated. However, most men starting TRT are not in high-risk age groups for prostate cancer, as it is more common in men over 70.

  • Current Guidelines:
    Routine PSA testing before starting TRT is no longer required unless there’s a history of prostate cancer.


2. Heart Health and TRT

Another common concern is that TRT increases the risk of heart attacks and other cardiovascular issues. This misconception arose from a poorly conducted study, but new research tells a different story.

  • TRT Is Cardioprotective:

    • TRT has been found to

      reduce the risk of heart attacks

      and overall mortality by up to

      30%

      in men with low testosterone.

    • It improves LDL cholesterol (bad cholesterol) levels, supports heart function in conditions like congestive heart failure, and promotes physical activity by boosting energy levels.

  • When Does Heart Risk Increase?

    • Men are more likely to experience heart attacks when testosterone levels decline, typically in their 60s and beyond. TRT restores testosterone to healthier levels, reducing this risk.


3. The "Roid Rage" Myth

The idea of "roid rage" has been popularized by media and anti-steroid campaigns. However, the speaker clarifies that this is not a concern with properly managed TRT.

  • TRT vs. Steroid Abuse:

    • TRT uses doses that mimic natural testosterone levels, unlike the excessive doses of illegal steroids, which can cause aggression.

    • The testosterone used in TRT is identical to the body’s naturally produced testosterone, ensuring compatibility and safety.

  • The Role of Estrogen Imbalance:

    • Any emotional changes, such as increased irritability, are typically linked to

      excess estrogen

      , which can occur if the body converts excess testosterone into estrogen (a process called aromatization).

    • This issue is easily managed with aromatase inhibitors, medications that block this conversion.


Why TRT is Safe and Effective

When managed by qualified professionals, TRT is safe for the vast majority of men. The speaker emphasizes the following benefits:

  • Heart Health:

    TRT reduces the risk of cardiovascular issues and boosts overall vitality.

  • Prostate Health:

    There is no increased risk of prostate cancer when using TRT appropriately.

  • Mental and Emotional Well-Being:

    TRT is unlikely to cause aggression or emotional instability when properly managed.

Exceptions:
TRT may not be suitable for men with conditions like excessive red blood cell production or a history of leukemia. In such cases, additional testing and alternative treatments may be recommended.


The Bottom Line

TRT offers a safe and effective solution for men struggling with low testosterone and its associated symptoms, including fatigue, low libido, and reduced energy. While concerns about prostate cancer, heart health, and aggression are common, modern research and clinical practice have debunked these myths, confirming TRT’s safety and benefits.


Take Control of Your Health with AlphaMD

If you’re considering TRT but have concerns, the experts at AlphaMD are here to help. With personalized care and evidence-based treatments, we ensure a safe and effective experience tailored to your needs.

Visit AlphaMD.org to learn more or schedule a consultation. Don’t let myths hold you back—discover how TRT can improve your health, energy, and quality of life.

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