Back to all Questions

question from a user

Hello, I had low T but normal LH and FSH levels last year. Sperm count and quality was also good. I started HCG monotherapy (1500 IU twice a week) around 2 months ago as I wanted to remain fertile, but I seemed to have some side effects on it, anxiety skin problems, etc. plus the doctor care was very bad so I switched to a private doctor. Now I am on Test E 125mg per week instead of HCG. My question is, I saw somewhere on this thread where you guys said that HCG doesnt work for fertility in primary hypogonadism. I do not know which type I have since LH and FSH are normal and so was sperm quality. A University clinic explained I may have functional hypogonadism, which to date I couldn't find out or understand exactly what this means. So I would like to start hCG alongside Test E for fertilty but I am not sure if it actually would work for me. I would greatly appreciate some info on this

AlphaMD's Answer


So, primary hypogonadism is typically diagnosed when LH levels are normal are high, and testosterone level is low. Basically, LH is the gas pedal telling the engine of the testicles to produce testosterone.

If your LH was low, we know hCG would work because it means that the pituitary gland was never pushing the gas pedal in the first place. hCG would take over for the pituitary gland in this case.The reality is, isolated primary or secondary hypogonadism these days is rare. Most men now have what is termed mixed hypogonadism. They have some pituitary dysfunction and some testicular dysfunction at the same time. The reasons for that are likely due to the daily exposures to endocrine disruptors in everyday modern life.

So hCG may work a bit in your case, as long as the testicles still have some function left. However, you may need a higher dose than others to get the same effect.

Ready to get answers?
Ask your own question today.

Get $30 off your first month’s order

Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.

Legal Disclaimer

This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.