question from a user

How does body weight and/or fat % come into play when determining dosage. I’ve noticed they don’t ask weight or body fat when considering treatment. It’s usually oh your test came back low let’s try 120/140mg to start for anyone/any size. For example 100mg for someone who is 150lbs vs. someone who is 250lbs would it follow logically that the 150lbs person respond better or have a higher test level during treatment simply due to lower weight/fat vs a much heavier person? Or does weight/fat have no bearing on how the individual’s body responds to the test. I don’t believe a practitioner would prescribe 200mg to an under 150 lbs person but I see lots of postings of people taking 200mg + but I’m assuming they are over 200lbs and/or have a high body fat %. Is they some sort of correlation or inverse relationship between weight/fat and extra test dosage that can be charted/graphed?

AlphaMD's Answer

There are some drugs that are doses based on weight, some on body surface area, and others on renal function. Testosterone is not one of them. Androgen receptors are located in many places, including adipose cells. However, it is a common misconception that people that have more fat have more fat cells. They don’t, the fat cells are just more full, like balloons. So a 150 lb person has the same number of androgen receptors at 250 lbs. Following that logic, they don’t need any more testosterone just because they are heavier.

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