question from a user
I have high triglycerides: 3.5 vs <1.5 reference. I think a part of that is certainly genetic as father has been on statins since early 30's. I was prescribed a oil soluble statin before TRT when levels were crazy (6.2 vs <1.5) but I paused it once I was on TRT which decreased it significantly. HDL is low (0.82 vs. >1 range) and chol in range (4 vs 3.5-5.5). Is medication recommended? If so, do you have a particular recommendation? I was recommended water soluble statins instead of oil soluble but also that statins don't necessarily help with triglycerides. Any particular diet recommendations? I've started fasting for 16 hours ish per day. I do love carbs like white bread though. Also since last blood test I've increased TRT dose slightly (from 50mg to 75mg cream applied scrotal daily). Will increased dose have much of an impact?
AlphaMD's Answer
Triglycerides are not affected by statins to any significant degree. Statins help with cholesterol, most specifically LDL. The primary way to treat triglycerides is through diet. You should eat healthy plant based fats and try to avoid processed meats, you should avoid sugar and heavily refined carbs (believe it or not carbs can raise triglycerides), and avoid alcohol. Exercising regularly and weight loss will help as well. TRT has actually been proven to have positive effect on lipids.
Most recent studies show that TRT lowers LDL cholesterol (the bad kind) and also lowers triglycerides. There does appear to be evidence that TRT also lowers HDL cholesterol (the good kind). Despite this, TRT seems to have an overall net positive effect for cardiac health due to the lowering of LDL and TGs.
Studies have proven that there is a positive correlation with TRT doses and its effects on the lipid profile, so higher doses would potentially lower your TGs further.
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