question from a user
I have seen that SHBG contains 60-80% of total testosterone i have been told by a few people that my only problem is high SHBG but im wondering if that much of total t is contained within SHBG if i lowered my SHBG right down to say 50% of what it is now to say more middle of the reference range lets say 20-25nmol/l would i lose a significant amount of my total testosterone which is already not overly high for my age? Also i believe gyno can happen during puperty quite often? Ive read that SHBG can rise as an attempt by the body to retain testosterone when its not being sufficiently produced?
AlphaMD's Answer
I would say this: Men often like to think of values at absolute rules and facts in medicine. However, this is not true, as all men are wildly different from each other in their own levels & things like age play a large role.Overall, and please don't think this is dismissive, don't get too caught up in SHBG when trying to figure out what to do. It's higher when you're younger, & it lowers as you age. Those things could very well have happened to you for that reason, it could be your genetics, or you could have abnormally high estrogen. The truth is you will never know for a 100% fact exactly what it was.What you can do is maybe get that baseline Estradiol and try out TRT to see if it helps with your issues. It will either do nothing (unlikely), raise your T to where you get the results you want, or balance out your T to SHBG ratios and to where you get the results you want.
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