question from a user
Thoughts on Kisspeptin and how it compares to hCG?
AlphaMD's Answer
Kisspeptin works in a different pathway. Kisspeptin is produced in the hypothalamus and acts upon KISS1 and GPR54 receptors to stimulate the release of several other hormones. It initiates the release of gonadotropin-releasing hormone (GnRH), which then stimulates the pituitary gland to release luteinizing hormone (LH) and follicle stimulating hormone (FSH).
hCG stimulates the testes directly to produce testosterone. There is a preference of hCG only because there is better evidence and data to suggest dosing and efficacy.
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