question from a user
AlphaMD's Answer
For the long term use of Enclomiphene I'll let one of my partners hop in on that tomorrow who is more knowledgeable on that aspect.
Tentatively it seems like Enclomiphene has less side effects than the combination drug Clomid, but at the end of the day the real question to me is what is someone looking to get out of either of them? Often times it seems like an attempt to look for an alternative to Testosterone use which can be rooted in misunderstanding just how useful and safe basic Testosterone is.
Enclomiphene has been proven to raise testosterone, which in and of itself has been proven to reduce the risks of heart disease, metabolic syndrome, and obesity.
As far as desmosterol, I can find no mention of any adequate studies that correlate enclomiphene and desmosterol levels in humans.
However, remember higher desmosterol levels have been proven to be beneficial for mental health and reducing the risk of Alzheimer's Disease.
Ultimately, making any conclusions at this stage without further research is just conjecture.
Desmesterol is the pre-cursor to cholesterol. Enclomiphene blocks the conversion of desmesterol into cholesterol by inhibiting the enzyme 24-dehydrocholesterol reductase. By blocking desmesterol, chol... See Full Answer
The arguments against long term use of Clomid: There are no good long-term studies on its use. There is only 1 study on its use for up to 3 years, and it showed that many men in that study had to drop... See Full Answer
So, we are a bit more conservative in that we don't feel like the science has proven any benefit for use of a SERM and TRT concurrently. We understand why this new practice of using enclomiphene is no... See Full Answer
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