Hypogonadal Men Treated with Clomiphene Citrate vs TRT
People are asking...
Would you recommend enclomiphene or clomiphene citrate before starting TRT?...
In some cases. We would only recommend it in men with secondary hypogonadism, as men with primary hypogonadism will not have any benefit from these medications because their testicles have stopped wor... See Full Answer
Thoughts on use of enclomiphene as opposed to TRT?...
The best case & results we've seen for it's use has been for men who have higher base Testosterone levels, aka relative hypogonadism TRT candidates. Since it is another medication which boosts your pr... See Full Answer
Hello I’m a 32 year old male with a history of anabolic steroid use at age 27. I’ve been having all the hallmark signs of hypogonadism Just had some r...
For you the answer would probably: Both are just fine. It more depends on your goals & what Sx you're feeling. First, it's good to find a provider to is chill with previous UGL use & can advise on wha... See Full Answer
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Purpose: We evaluated the relative prevalence of secondary polycythemia in hypogonadal men treated with clomiphene citrate or testosterone replacement therapy.
Materials and methods: In this retrospective, multi-institutional study, we included 188 men who received clomiphene citrate and 175 who received testosterone replacement therapy with symptomatic hypogonadism. The overall prevalence and ORs of secondary polycythemia for clomiphene citrate treatment vs testosterone replacement were primarily measured, as were baseline characteristics. Subset analysis included polycythemia rates for different types of testosterone replacement therapy.
Results: Overall, men on testosterone replacement therapy were older than clomiphene citrate treated men (age 51.5 vs 38 years). Men on testosterone replacement had longer treatment duration than clomiphene citrate treated men (19.6 vs 9.2 months). For testosterone replacement therapy and clomiphene citrate the mean change in hematocrit was 3.0% and 0.6%, and the mean change in serum testosterone was 333.1 and 367.6 ng/dl, respectively. The prevalence of polycythemia in men on testosterone replacement was 11.2% vs 1.7% in men on clomiphene citrate (p = 0.0003). This significance remained on logistic regression after correcting for age, site, smoking history and pretreatment hematocrit.
Conclusions: The prevalence of polycythemia in men treated with clomiphene citrate was markedly lower than that in men on testosterone replacement therapy. The improvement in absolute serum testosterone levels was similar to that in men on testosterone replacement. There is no significant risk of polycythemia in men treated with clomiphene citrate for hypogonadism.
Have a question? Ask us.
At AlphaMD, we're here to help. Feel free to ask us any question you would like about TRT, medical weightloss, ED, or other topics related to men's health. Or take a moment to browse through our past questions.
People are asking...
Would you recommend enclomiphene or clomiphene citrate before starting TRT?...
In some cases. We would only recommend it in men with secondary hypogonadism, as men with primary hypogonadism will not have any benefit from these medications because their testicles have stopped wor... See Full Answer
Thoughts on use of enclomiphene as opposed to TRT?...
The best case & results we've seen for it's use has been for men who have higher base Testosterone levels, aka relative hypogonadism TRT candidates. Since it is another medication which boosts your pr... See Full Answer
Hello I’m a 32 year old male with a history of anabolic steroid use at age 27. I’ve been having all the hallmark signs of hypogonadism Just had some r...
For you the answer would probably: Both are just fine. It more depends on your goals & what Sx you're feeling. First, it's good to find a provider to is chill with previous UGL use & can advise on wha... See Full Answer
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