Back to all Questions

Questions about ED

Find answers to commonly asked questions about ED, administration, and benefits.

A patient asked

Is there an alternative to HCG in respect to keeping the testes from shrinking? Ive also read anecdotal reports from some that HCG has helped them ke...

AlphaMD's answer

There are not good alternative for teste size, or at least none as good as HCG with as few negatives as it has other than price.

A patient asked

My labs are dialed in on TRT but I still feel like I have room for improvement. Whats a good starting dose of HCG to help improve libido further and h...

AlphaMD's answer

Typical low end dosing for hCG is 500IU/wk. “Start low and go slow” is what they teach in med school, and I would suggest that with the addition of an...

A patient asked

Does TRT help venous leak and erectile dysfunction in general?

AlphaMD's answer

In general, yes. It increases corpus collosum blood flow. It helps by bringing in more blood flow, though to a lesser extent slowing venous outflow. B...

A patient asked

HCG benefits more than just fertility. It also benefits mood and sensitivity, but too much can cause someone to crash. I'm guessing it causes E to sp...

AlphaMD's answer

Awesome to hear that, those are great outcomes. Yes, it can cause E spikes as well at any level depending on the person. That more has to do with how ...

A patient asked

Do you have any patients where trt has made erection quality worse? I’ve been on trt for 4 months with all bloods in range but feel like my erection q...

AlphaMD's answer

So, hormones are only a small part of erection quality, though an important part. As a general rule of thumb, if you get morning wood, but have ED dur...

A patient asked

What injection frequency do you typically see the most success with your patients? 1x weekly, 2x weekly, EOD, ED, etc.

AlphaMD's answer

In our practice, ~90% of men get best results with twice weekly injections. The remaining ~10% have different injection frequencies ranging from once/...

Don't see your question?

Please send us your question and we will get back to you as soon as possible. Normally within 2 business days.

A patient asked

Do you offer peptides and if so can you talk a little bit about which ones you offer and the possible benefits?

AlphaMD's answer

We do, though they are more tightly focused than a full on peptide provider. This is because we can only work with peptides that are available from ph...

A patient asked

is there a big difference in injecting ,same weekly dose, once a week vs twice a week vs three times a week vs EOD vs ED. I have tried all and don't...

AlphaMD's answer

Generally we don't have enough data to compare between the two, as you'd really need a man who has done both & testing multiple times with both at th...

A patient asked

if someone if having high E2 symptoms, poor sex drive, ED issues, water retention, High BP, high emotions, would you recommend lowering the dose or a...

AlphaMD's answer

It depends. So long as they still have relief of their low T symptoms on a lower T dose, then typically lowering the dose is the correct first step to...

A patient asked

What doses and ratios (testosterone:nandrolone) do you normally use for TRT regiments? And how often do you forgo testosterone completely in favor of ...

AlphaMD's answer

A normal testosterone:nandrolone protocol is dosed at a 2:1 ratio.

A patient asked

Is any symptom considered more relevant for TRT than others? I.e. low libido versus ED versus muscular issues

AlphaMD's answer

Some symptoms are more directly treated by TRT than others, and that makes them more relevant to diagnose it. Low energy, low libido, difficulty losin...

A patient asked

Who are your pharmacy’s? How do you choose them?

AlphaMD's answer

In digital TRT, it's usually best to work with a compounding pharmacy or a pharmacy designed to work with businesses. Local pharmacies like Walgreens...

A patient asked

How do you handle libido problems? If testosterone and estradiol are both in range, where do you look next? DHT? Prolactin? I am currently dealing wi...

AlphaMD's answer

Libido issues can unfortunately be difficult to pin down sometimes because there are many factors, both intrinsic and extrinsic, that affect it.

A patient asked

What do you recommend for PE. I can't stand it. I am using desensitization but still not much help. Also takes aot of preplanning to be effective. The...

AlphaMD's answer

For premature ejaculation, medically speaking you have a couple options. But it is important to know, the FDA has not approved any medications for PE,...

A patient asked

Anything to try other than cabe ror P5P to lower prolactin? Since starting TRT I've had a really difficult time reaching orgasm. Erections are no prob...

AlphaMD's answer

Pramipexole works well to control prolactin. It has been proven to help both achieve orgasm as well as with the refractory period after orgasms.

A patient asked

I'm 37. I went to a clinic with my complaints and a hormonal test was done: Fsh 2.69mIU/mL Lh 7.28mIU/mL Prolactin 3.95ng/mL Testosterone 18.0nmol...

AlphaMD's answer

Your doctors didn’t lie in saying your labs don’t show anything abnormal. But they won’t always because what is “normal” is based on population avera...

A patient asked

Have you noticed some men need large fluctuation in levels to get a libido increase on trt? SHBG aside, keeping levels consistent with pinning daily ...

AlphaMD's answer

We have had a few men where that is the case, though I would definitely not say it is the rule. The primary driver of libido in men is DHT, and more D...

A patient asked

Estradiol 20.4 T 175.8 FSH 3.9 LH 1.0 Prolactin 5.8 Thsr 1.59 Xt wbc 5.3 35m 170lb 16 % bf decent sleep , clean eating no alcohol Fatigue sex drive ha...

AlphaMD's answer

Your LH is low and your FSH is on the lower end as well. This suggests you may have secondary hypogonadism.

A patient asked

Estradiol 20.4 T 175.8 FSH 3.9 LH 1.0 Prolactin 5.8 Thsr 1.59 Xt wbc 5.3 35m 170lb 16 % bf decent sleep , clean eating no alcohol Fatigue sex drive ha...

AlphaMD's answer

Your LH is low and your FSH is on the lower end as well. This suggests you may have secondary hypogonadism.

A patient asked

If a person would take HCGs the preserve fertility, how many injections can he expect to do weekly on a combo of TRT and HCGs Also, regarding libido,...

AlphaMD's answer

Someone looking to maintain fertility by using hCG while on TRT would typically dose at a minimum of 500 IUs/wk, with improving sperm levels with incr...

A patient asked

What are the best supplements to add to TRT to increase libido?

AlphaMD's answer

Horny Goat Weed is cheap, OTC, generally well tolerated, and works good for most men. I personally use it daily and can notice a solid drive differenc...

A patient asked

TLDR: high output / high stress life. Physically and mentally. Last 2 years feeling sluggish, burned out, and find doing challenging things extremely...

AlphaMD's answer

We very often here "I have been feeling like shit for 6 months for 2 years, I have symptoms of low T" for all patients seeking if TRT is right for the...

A patient asked

36 M - 4 weeks into treatment. 60MG test cyp injection Tuesdays and Fridays. Started w T level around 280 - all typical symptoms. Low energy, moodines...

AlphaMD's answer

Check out this timeline we give to our patients:

A patient asked

Does trt improve or reduce sperm count?

AlphaMD's answer

Exogenous testosterone will always have a detrimental effect on sperm count.

A patient asked

Can you comment on the distinction between TRT cream and injections? Do you find cream has better dht conversion? Does this mitigate some of the libid...

AlphaMD's answer

In general we find that libido & erectile function are improved through either method for any man suffering from hypogonadism. There are a few cases w...

A patient asked

I've been noticing a lot of fatigue and brain fog the day before I take my Testosterone Cypionate. Is this just in my head since the half-life for Tes...

AlphaMD's answer

It is realistically closer to 4 days, and if you can tell a difference the day before your normal shot it would be perfectly fine to change to three t...

A patient asked

Hi, I’m 25 years old. Test is 404. I work out 5 days per week, am pretty lean and fit and healthy I had previously considered TRT but ultimately turn...

AlphaMD's answer

A few things to note:

A patient asked

What’s your take on ED issues with guys on TRT? What’s the most common cause? High Estradiol? Low T? Where’s the sweet spot for E levels? 20-30 is wha...

AlphaMD's answer

ED is often more complicated than just hormones. But when it comes to sex hormones, low T, high/low E2, and high prolactin are common culprits.

A patient asked

What’s your view on different esters? I’ve seen a number of posts and YouTube videos claiming libido and erections returning and better energy when s...

AlphaMD's answer

Different Esters can have impact on the actual average dosing you experience. That is why even if you take Test C & Test E at the same amount per wee...

A patient asked

Does TRT benefit erection quality?

AlphaMD's answer

Yes, generally the three main reasons people start TRT are: Energy/motivation, fat loss issues/muscle loss, and libido/erectile function.

A patient asked

How effective is tadalafil paired with TRT? Does it helps to reduce e2, and if so, do you recommend? And what daily dose to see synergy?Does it helps...

AlphaMD's answer

It is common to combine the two when the initial symptoms of low Testosterone include low libido or ED. We tend to hold off on adding it right away to...

Get $30 off your first month’s order

Enter your email address now to receive $30 off your first month’s cost, other discounts, and additional information about TRT.

Legal Disclaimer

This website is a repository of publicly available information and is not intended to form a physician-patient relationship with any individual. The content of this website is for informational purposes only. The information presented on this website is not intended to take the place of your personal physician's advice and is not intended to diagnose, treat, cure, or prevent any disease. Discuss this information with your own physician or healthcare provider to determine what is right for you. All information is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. The information contained herein is presented in summary form only and intended to provide broad consumer understanding and knowledge. The information should not be considered complete and should not be used in place of a visit, phone or telemedicine call, consultation or advice of your physician or other healthcare provider. Only a qualified physician in your state can determine if you qualify for and should undertake treatment.