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Questions about HCG (Human Chorionic Gonadotropin)

Find answers to commonly asked questions about HCG (Human Chorionic Gonadotropin), administration, and benefits.

A patient asked

Does HCG make sex better? Not necessarily having issues currently with my TRT dose but anecdotally heard it increases sensitivity and makes sex better...

AlphaMD's answer

There has been anecdotal reports of this by some men, though we tend to think this is more about finding the right hormone levels rather than the addi...

A patient asked

Is there an alternative to HCG in respect to keeping the testes from shrinking? Ive also read anecdotal reports from some that HCG has helped them ke...

AlphaMD's answer

There are not good alternative for teste size, or at least none as good as HCG with as few negatives as it has other than price.

A patient asked

I just had 6 week bloods done. e2 was 48. SHBG must be crashed because my free T was 255. Obviously an e2 of 48 is unlikely to cause any puff or itchi...

AlphaMD's answer

Well, to break things down, when starting TRT you should generally not be adjusting your routine or adding medications until the 7-8 week mark when yo...

A patient asked

Are there any downsides to using hCG?

AlphaMD's answer

Generally no, it is fairly safe. There are a few niche interactions which may have it tip your Estrogen up or such, but that's usually more controlled...

A patient asked

After being on TRT for a while, is there any way to increase the sperm count in case you want to have a child? Number one reason I haven't started TRT...

AlphaMD's answer

Taking hCG concurrently while on TRT can maintain sperm production.

A patient asked

Empower is great for compounding. And as for the generics. I guess you would just trust the ones that you could actually find on the FDA website? I gu...

AlphaMD's answer

We trust the large chains more just like you suggest, and like the poster below states, since Testosterone is such a safe product & the production isn...

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A patient asked

Does your clinic ever use AI's with clomid, and have you noticed any benefits? Disclaimer: obviously not asking for medical advice. Just discussing.

AlphaMD's answer

For the patients that we have on Clomid, most of them require the use of an AI. The benefit of adding the AI helps reduce high E2 symptoms which inclu...

A patient asked

Does pregnyl lose potency after 60 days?

AlphaMD's answer

Technically yes, but realistically no.

A patient asked

Im 32 can I do hcg alone or trt with hcg and still gain permanent penis size gains? Did anyone do this before? Or with a dht cream with hcg ?

AlphaMD's answer

The only study that showed gains with penis size on hCG was done in fully grown men with micropenis. It does not cause penis growth outside of that su...

A patient asked

Does the amount one takesTest correlate to the amount they should take with HCG? Lets say you take only 40mg a week should you take the same amount of...

AlphaMD's answer

HCG dose is independent of what TRT dose you are on. Basically, when on TRT, the LH receptors are just hanging out, doing nothing. They are just waiti...

A patient asked

What have you found to be best for fertility with your patients, clomid or something like hcg+fsh? Obviously people react differently on different med...

AlphaMD's answer

With our patients, we have had more success with hCG. This may have to do with the fact that more of our patients prefer hCG to clomid. Every patient ...

A patient asked

Is hcg necessary for the nuerochemical cascade that you wouldn’t get if you just took trt?

AlphaMD's answer

Necessary? Not really considering the neurosteroids that are affected by TRT can actually be taken orally. Pregnenolone (and its derivative allopregna...

A patient asked

My urologist is starting me off with 2000 unit of HCG a week.. my levels are in the 200s. Canadian. Any chance I notice any difference? Is it safe fo...

AlphaMD's answer

If you have secondary hypogonadism (pituitary function poor, normal testicular function), then hCG may double your total testosterone. If you have pri...

A patient asked

Is there any way to reduce HCT without donating blood constantly? I had high numbers from the beginning and it seems to keep climbing. We have reduce ...

AlphaMD's answer

Sadly dose reduction is one of the main raise to help lower this if you don't want to deal with blood donations. There may be some OTC options as well...

A patient asked

Maintaining testicular size and strength are important to me should I start TRT, and I hear HCG is the way to do that. Are there any alternatives if H...

AlphaMD's answer

Adding hCG to TRT essentially “keeps the factory working”. It counteracts the most of the testicular shutdown that occurs on TRT, and at sufficient do...

A patient asked

If I have too low E2 while I am on TRT would HCG a good option to slightly increase it? I tend to have low E2 with sometimes under 10 even though my ...

AlphaMD's answer

Yes, hCG does result in a higher aromatization rate than exogenous testosterone. This is because when you are already on TRT, your body recognizes tha...

A patient asked

I’m convinced that HCG ruined my TRT experience. Unfortunately my clinic started me on both at the same time. Experienced sides immediately that last...

AlphaMD's answer

Many men have side effects from hCG. This is why we never advocate for starting hCG and TRT at the same time. Dial in the TRT first and find your opti...

A patient asked

I have been on Test CYP for 6 months and now want to come off. I have 4 5000iu bottles of HCG. What is the typical dOSE per week people are taking to ...

AlphaMD's answer

Reading this post has me confused on something I thought I was clear on. Hope my sophomoric question doesn’t rile anyone up.

A patient asked

Can HCG be used alongside Clomid for fertility proposes? For example 1500iu EOD and 25mg Clomid ED until conception.

AlphaMD's answer

There are some providers who recommend that, though bear in mind HCG and the LH produced from Clomid use compete for the same receptor.

A patient asked

What is a common dosage of HCG for someone who is taking 200mg of Testostorone Cypinate weekly? On forums I have seen as little as 100mg HCG 2x a wee...

AlphaMD's answer

HCG dosing is determined independent from Testosterone levels or Testosterone dosing, and is generally based on desired use case. If your goals are co...

A patient asked

Do hematocrits ever level out without donating blood? I was on 100 mg once a week , my levels the day before injection was always about 580 that being...

AlphaMD's answer

They can, yes. There is no exact answer for hematocrit to dosing ratio to look at, because this one is totally dependent on the individual. Some men c...

A patient asked

Is HCG better than Enclomipine?

AlphaMD's answer

To be very general, yes. There's many aspects to consider but the biggest one for us is that IGF-1 can be suppressed heavily on Enclomiphene & it isn'...

A patient asked

I see many people say that HCG can raise estrogen in a disproportionate amount when compared to just testosterone alone. However, I’ve never seen any ...

AlphaMD's answer

There are no studies on this. It is primarily something noticed clinically. For example, I saw a patient last week who was on 150mg/wk of TRT. His E2 ...

A patient asked

My total T was 293 when I started TRT at 28 years old. Been in 120mg weekly. Injecting twice week with no side effects other than body acne do too ge...

AlphaMD's answer

If you wanted to come off of TRT then you'd want to work with your TRT provider. You could likely come off with HCG dosing and potentially a short sti...

A patient asked

Hi! I’m doing HCG mono 3500 UI / week. 3 mg Anastro / week and 50mg clomi 3x / week. My T is at 1050 and E2 at 39. Without anastro I was with 90 E2 f...

AlphaMD's answer

That is indeed a very high dose of anastrozole.

A patient asked

I’m on HCG monotheraphy medication called Ovitrelle which contains choriogonadotropin alpha 6500 IU (3x/week). I see that it’s potency is way higher i...

AlphaMD's answer

Ovitrelle is slightly different than other forms of rHCG, but is similarly dosed. That is a higher dose than usual for hCG monotherapy.

A patient asked

Just out of curiosity, why is some of the Hcg prescribed for intramuscular injections by regular docs? My understanding is that it works better subcu...

AlphaMD's answer

hCG can be either SQ or IM. Most men will see better absorption and synthesis by the body via SQ. SQ also won't ruin arm or leg day or cause you to ha...

A patient asked

i've been on TRT for about a year, I have already had children, so I don't need my fertility. I'm not taking HCG and from my understanding because I d...

AlphaMD's answer

In your case, we wouldn't recommend HCG for you. Mostly because you don't want the fertility & because it sounds like you have the benefits you need f...

A patient asked

Can you give an example of where HCG monotherapy would be suitable and the dosing strength and frequency?

AlphaMD's answer

The most important aspect of choosing whether hCG monotherapy is appropriate is first determining if you have primary or secondary hypogonadism. Prima...

A patient asked

Is there any long term risk associated with hcg use?

AlphaMD's answer

Generally HCG is fairly safe to work with long term, and many men enjoy low doses of it alongside their traditional TRT.

A patient asked

How does HCG affect total t, free t, and estrogen on top of current trt dose? If there is a large difference, would it be beneficial in some cases to...

AlphaMD's answer

HCG can effect this in some very specific cases. Usually it is if the HCG dose is moderate to high & the patient in question had a higher baseline Tes...

A patient asked

I'm on a 2000 IU, 3x a week (6k...) dosage of hcg after having done trt for 2 years. The hcg does totally make me feel better, but my dosage feels a b...

AlphaMD's answer

That is a relatively high dose of HCG, though if you are trying for active conception, that could be fine until it occurs. After that, it may be wise ...

A patient asked

My labs are dialed in on TRT but I still feel like I have room for improvement. Whats a good starting dose of HCG to help improve libido further and h...

AlphaMD's answer

Typical low end dosing for hCG is 500IU/wk. “Start low and go slow” is what they teach in med school, and I would suggest that with the addition of an...

A patient asked

My Dr has only prescribed HCG after I'm done with my vial of Testosterone, is that normal? To only take it between my vials of testosterone? My proto...

AlphaMD's answer

No, that would not be very normal. It is much more common to be on a consistent safe dosing of Testosterone constantly & a lower dose of HCG semi-cons...

A patient asked

How much HCG is it good for me to start with being on 250ml of test? Plz conservative doses only I don’t want to over do it

AlphaMD's answer

If you're looking for basic maintenance doses of HCG, 500 units weekly is a very standard approach for baseline fertility & testicle size. At 250mg T ...

A patient asked

What are your thoughts on an hCG starting dose? And how long before I would notice a difference for my trial? And since I’m asking questions… I know ...

AlphaMD's answer

Starting dose for hCG is typically 500-750IU/wk, often divided into 2 or 3 shots per week.

A patient asked

'm currently on TRT (cypionate 110ml/week) for really low T that presented itself after a chronic Rocky Mountain Spotted Fever and Anaplasmosis infect...

AlphaMD's answer

It is interesting that is has that effect for you, and we may suggest experimenting with the dosing & frequency further to see if it can provide that ...

A patient asked

What should be the normal dosage of HCG while on my cycle, here's what I'm dosing 2cc per week (800mg) need to know right dosing nuts are shrinking wa...

AlphaMD's answer

For HCG dosing, it is done by units. If you are on 800 units weekly, that should be fine for a moderate dose to maintain things as they are. If you're...

A patient asked

If experiencing symptoms of high E when HCG is introduced (I’ve done just Test 200/weekly no sensitive nipples) but when HCG is introduced I got them…...

AlphaMD's answer

You can lower the dose. Spreading the dose out won’t change much considering the half-life is 3.5 days, so doing it more frequently won’t change much.

A patient asked

If children aren’t in the immediate future is it ok to discontinue HCG use until ready to conceive? Or metaphorically speaking .. is it smarter to ke...

AlphaMD's answer

Due to the price of HCG & how it tends to work, many men elect to go through TRT without it until the time comes for conception. We generally ask for ...

A patient asked

What are your thoughts on enclomiphene without TRT and do you see it gaining FDA approval anytime soon?

AlphaMD's answer

This is very similar to another question so I will copy/paste that answer.

A patient asked

What are your thoughts on HCG mono-therapy? What dosage would you recommend?

AlphaMD's answer

In general it is fairly safe, and if you are suffering from low Testosterone & don't want your TRT to be in the form of Testosterone injections, it i...

A patient asked

How would you treat someone with very low SHBG and high estrogen symptoms? Assume patient is taking a large amount of AI already.

AlphaMD's answer

Generally adjust their dosing frequency to be more frequent to reduce overall spikes which may cause aromatization, switch from IM to subq because it ...

A patient asked

I’ve read that subq tends to aromatize more due to conversion in fat. Is that true?

AlphaMD's answer

No, it is not truly. In almost all cases it causes overall less aromatization to occur because that action is in response to when your body detects T ...

A patient asked

I've been in TRT for near 10 years. No HCG as wife said no kids. Now she wants a child. Can I stay on my trt and add HCG? Or best to come off? I don...

AlphaMD's answer

It depends on your timeline. If there is any rush, the fastest route to fertility is quitting TRT. However, it only takes the majority of men 90-120 d...

A patient asked

Is it possible to order just the HCG from you, if I receive my TRT from a different clinic?

AlphaMD's answer

This would be possible, though the pricing for this would be different than the traditional TRT costs. (Higher, since HCG costs more than Testosterone...

A patient asked

What if my baseline was around 250-280, would dropping the HCG disrupt my current levels with the HCG by a lot you think?

AlphaMD's answer

Not likely by that much. While hCG does add to the total testosterone level while on TRT, the TRT is still suppressive to a degree that is rarely over...

A patient asked

If possible. How common are blood clots with HCG? And does HCG directly increase hypercoagulability by itself or indirectly via increased Testosteron...

AlphaMD's answer

They are not a common side effect of the medication at all, nor is it considered common to Testosterone either. If it were to impact it, it would be v...

A patient asked

I’m already splitting HCG & test doses into 3x/week injections, IM test and SubQ HCG. Which one were you referring to when you suggest switching to Su...

AlphaMD's answer

Your Testosterone specifically for Subq. Testosterone is absorbed slower via subq than IM, resulting in an overall more even level & lower Testosteron...

A patient asked

HCG benefits more than just fertility. It also benefits mood and sensitivity, but too much can cause someone to crash. I'm guessing it causes E to sp...

AlphaMD's answer

Awesome to hear that, those are great outcomes. Yes, it can cause E spikes as well at any level depending on the person. That more has to do with how ...

A patient asked

How far in advance should one start HCG before trying to conceive?

AlphaMD's answer

Generally 3-6 month's heads up is what we suggest, 3 months is the minimum time it takes for a sperm to reach maturity.

A patient asked

Why is hCG being restricted? It has personally been extremely helpful for me and I dread a day where I can get it… I just paid 250 for 2x 6000iu vials...

AlphaMD's answer

The "why" aspect of it comes down to likely overregulation but really some of these small changes can have some pretty large impact on the whole proce...

A patient asked

So what are some risks of trt dose for rest of life besides not being able to have kids really just trying to understand ? Thanks in advance

AlphaMD's answer

Risk factors for traditional managed TRT are quite low, it is one of the lowest cost malpractice medical fields to put it into perspective. Since you ...

A patient asked

I have a brand new vial of HCG I need to reconstitute. Would you recommend that I drop the progesterone or continue it while I reintroduce HCG? (Regar...

AlphaMD's answer

While we recommend you speak to your doctor regarding your protocol, our recommendation would be to take only hCG or progesterone; not both. Taking bo...

A patient asked

What would TRT cost with the addition of hcg? How many months of prescription do you send out at once and is it delivered to my door or do I go to a ...

AlphaMD's answer

Generally HCG is $300 at the time of order/reorder and we send out 10,000 units at a time. Typical dosing is 500-1000 units weekly depending on goals,...

A patient asked

When the HCG gets here should I do em both? I've seen them used together with a mixed bag of opinions. It's just 1 vile I will not be getting anymore ...

AlphaMD's answer

Once the hCG arrives, you should discontinue the gonadorelin.

A patient asked

So I've been on TRT for 6 months, my clinic doubled my dose when I was at 615 with normal E2 levels then 3 months later. I'm only at like 718 and my E...

AlphaMD's answer

You already paid for it, there is no harm in trying it. It’s true, gonadorelin is a poor substitute for hCG, and has little benefit for this purpose, ...

A patient asked

This is two years of 6 month interval tests including FSH and LH Here’s a summary of my Total Testosterone and Free Testosterone numbers over time: ...

AlphaMD's answer

Your LH levels are lower than expected for your T levels for true isolated primary hypogonadism. You may have some mixed hypogonadism (both testicular...

A patient asked

Interesting that you say that because I found that my 3-4 years of elevated blood pressure have gone away ever since introducing one pump of progester...

AlphaMD's answer

While we recommend you speak to your doctor regarding your protocol, our recommendation would be to take only hCG or progesterone; not both. Taking bo...

A patient asked

At 1000 iu weekly, are there any long term side effects of the body no longer responding and producing LH?

AlphaMD's answer

As answered in another question today, long term use of hCG does carry the risk of downregulation of the LH receptor. So we always recommend a "drug h...

A patient asked

What would it cost with the addition of hcg? How many months of prescription do you send out at once and is it delivered to my door or do I go to a ...

AlphaMD's answer

Generally HCG is $300 at the time of order/reorder and we send out 10,000 units at a time. Typical dosing is 500-1000 units weekly depending on goals,...

A patient asked

If your LH levels are low as well as your testosterone levels, would you be a good candidate for hcg as opposed to trt? And do your levels stay elevat...

AlphaMD's answer

For those with low LH (secondary hypogonadism), hCG monotherapy can work well to raise testosterone. Once you stop treatment, levels will return back ...

A patient asked

If the goal is to prevent permanent testicular atrophy with no immediate plans to have a kid, would the advice be to go on HCG every 3 months for a 3-...

AlphaMD's answer

For many men the easy solution is to do 3 months on & 3 months off, or just stay on a low dose long term. A simple 500 units weekly tends to be a soli...

A patient asked

1. Disregarding systemic effects, are there any downsides for your hair specifically to taking oral dutasteride? I'm fortunate to have zero signs of h...

AlphaMD's answer
A patient asked

I know someone who is on 200 mg a week. Went from 290 to 1000 at trough, but they don't feel any different. Test is from a clinic in USA. Thoughts?

AlphaMD's answer

It sounds like they may either be on too much for what they need & much is aromatizing to Estrogen, or they preemptively gave them an AI that was too ...

A patient asked

Is 496 too low at 20? Am i in a disadvantage?

AlphaMD's answer

When looking at a textbook definition of Testosterone levels, you would not be considered low. However, you would still be within an acceptable range ...

A patient asked

Cold turkey to quit testosterone?

AlphaMD's answer

We would generally advise against this, as it is fairly easy to work with either HCG, Clomid, or Enclomiphene to make the transition off of TRT easier...

A patient asked

What are your thoughts on theoretical long term effects on enclomiphene or were the studies not designed or powered to look for adverse events? Clomid...

AlphaMD's answer

For the long term use of Enclomiphene I'll let one of my partners hop in on that tomorrow who is more knowledgeable on that aspect.

A patient asked

Why does enclomiphene raise testosterone levels, but the testosterone doesn’t seem to be absorbed by the body, thus not relieving any symptoms of low ...

AlphaMD's answer

So, this may be a bit of a two part answer. A bit candid if you're okay with that.

A patient asked

Does anyone "time" TRT use according to their endurance schedule? That is, I *know* roughly when I'm going to bottom out -- during the two hardest mon...

AlphaMD's answer

From personal experience, I have raised my Testosterone consumption during periods I know it was dropping due to reasons like the above. However, I am...

A patient asked

Been on TRT since November. My wife and I would like to eventually have kids but we won’t be ready to start trying for 2-3 years. I know some doctors ...

AlphaMD's answer

That is generally how we approach this subject as well.

A patient asked

How do you handle libido problems? If testosterone and estradiol are both in range, where do you look next? DHT? Prolactin? I am currently dealing wi...

AlphaMD's answer

Libido issues can unfortunately be difficult to pin down sometimes because there are many factors, both intrinsic and extrinsic, that affect it.

A patient asked

I have been seeing more advice on replacing HCG with 2x/week enclomid (5-12.5mg). What are the pros/cons if this scheme?

AlphaMD's answer
A patient asked

What are your thoughts on HCG along with TRT? 41 yo started trt about 6 months ago, and considering HGC. What are some advantages, and disadvantages? ...

AlphaMD's answer
A patient asked

Why is it that Clomid, despite raising T levels, isn't really that effective? I've seen countless people on here say that their Free and Total T leve...

AlphaMD's answer

People have this question often. And the answer is Clomid is a medicine, testosterone is not.What I mean by that is Clomid (clomiphene) is a foreign s...

A patient asked

I’m on week 8 of 140mg / week and the original prescription included hcg. Trt clinic wants to wait until post 8 week labs to then introduce hcg, not f...

AlphaMD's answer

So our opinion on HCG is that it's really expensive to produce in the USA & thus they're probably charging and arm & a leg for it. If you're not takin...

A patient asked

When (or what circumstances) would you recommend clomid over testosterone?

AlphaMD's answer

The most common case is when a patient insists on it because they've read about the medication and really want to take a pill instead of do an inject...

A patient asked

I didn’t like HCG so my dr switched me to enclomiphene, which I tolerate better. I recently purchased some clomiphene citrate, is that ok to take for ...

AlphaMD's answer

Are you on TRT as well or are you doing SERM mono therapy?

A patient asked

Just started 200 mg split in 2 doses a week. Felt great first few week with high sex drive, full erections, morning wood, and strength in the gym. Wee...

AlphaMD's answer

There is a very common phenomenon around the 6 week mark of TRT, where some of the benefits seem to diminish. No one knows why that is, though we beli...

A patient asked

32 years old, not done having kids. T level at 294 with no energy, depressive tendencies and up and down libido. Doctor has prescribed me Clomid. I'v...

AlphaMD's answer

Many men still produce enough sperm while on TRT and hCG to get a woman pregnant.

A patient asked

Why is it that Clomid, despite raising T levels, isn't really that effective? I've seen countless people on here say that their Free and Total T level...

AlphaMD's answer

Although we replied in the other thread, just going to post it here incase it helps someone:

A patient asked

Can you have one of your providers look at my most recent thread (which includes bloodwork) See if they can give correct diagnosis. Would be a chance ...

AlphaMD's answer

Please refer to our disclaimer that we are not your doctor, and this advice is general and not meant to constitute a treatment plan.

A patient asked

I was reading hcg alone wasn’t a viable option according to the gurus of Reddit. But then again it’s the internet. Any comment on that ? Also there wa...

AlphaMD's answer

It's certainly more of a short term option as a stand alone, the addition of Testosterone will always be better, but trying to provide a benefit while...

A patient asked

I still want to have kids and want to avoid anything that could possibly shut me down all together. Which treatment is best for me ?

AlphaMD's answer

It depends on when you want to have children. If your intent is to conceive in the next 12 months, you should choose hCG alone or a SERM like enclomip...

A patient asked

And can you write scripts that can be use for insurance? Like thryroid meds and hcg?

AlphaMD's answer

We do sometimes work with local pharmacies instead of compounding pharmacies when patients ask for it. It's just important to note that your insurance...

A patient asked

What are your opinions on Maxum King’s and Hims treatment and the clomid tabs? Is clomid a beginners route to see if supplements are the right path? ...

AlphaMD's answer

We're not the biggest fan of clomid itself. It does raise Testosterone levels but lowers IFG-1 levels, which is one of the larger benefits of having ...

A patient asked

Is HCG recommended even if fertility is not a concern?

AlphaMD's answer

The very short answer: No. It does not provide much benefit that normal Testosterone wouldn't as well, and is current very expensive. That said, if so...

A patient asked

Currently on trt cream, no hcg. Talking about starting family with my wife, wondering what the best way to boost fertility without coming off would be...

AlphaMD's answer

Without coming off of TRT, then hCG would be the typical recommendation. This will raise intratesticular testosterone levels and restart sperm product...

A patient asked

I realize you need to answer in a generalization, but I’m searching for answers on nipple sensitivity and puffiness around the nipple. Currently no lu...

AlphaMD's answer

hCG aromatizes more that testosterone does. Your likely having elevated estradiol from that. You should speak with your doctor, but your options are t...

A patient asked

I’m 31, 6’2”, and 345lbs. I had back surgery last year and I was about 260 and athletic before I got injured 10 years ago. I’m fairly strong (I do som...

AlphaMD's answer

Well, you have low total and free T. Technically, your FSH and LH should be higher in an effort to get your testicles to work harder. But FSH and LH a...

A patient asked

What added benefits does HGH (not peptides) bring to a TRT routine?

AlphaMD's answer

HGH Carrie’s the benefits of improving nitrogen retention beyond that of testosterone. It increases IGF-1 levels to a greater extent than testosterone...

A patient asked

Can you get hcg mixed into TRT cream? Or does hcg need to be injected?

AlphaMD's answer

hCG does cannot be absorbed through the skin. It also cannot survive first pass metabolism, so it cannot be taken orally either.

A patient asked

Does it make sense to not take HCG currently if your plan to have kids is in, let's say, 5 years? Instead, you start taking HCG after those 5 years to...

AlphaMD's answer

Yes, that makes sense. Every study on the subject has shown that hCG causes a return of fertility. In fact, 75% of men on TRT become fertile while als...

A patient asked

In terms of injecting, how many times in a week or month would patients typically inject HCG?

AlphaMD's answer

Typically you'd do injections twice weekly if you're going to be on TRT anyways, as you inject Testosterone twice weekly most of the time anyways. Giv...

A patient asked

Does HCG effectively mean I would still produce my own T as well as gain T naturally as I take TRT? Say for example, im on TRT and HCG, I’m going to t...

AlphaMD's answer

Not quite. A good way to think about it is that the main purpose & effect of HCG is to "prime" the testes for production, which will do a good job of ...

A patient asked

42yrs old. I took Boron and DHEA for about 7-8 years and T levels were in the mid 400's and felt good. Recently it stopped working as well so I stopp...

AlphaMD's answer

It would depend on your test results, but things like Clomid increase your Testosterone by an amount of your base ability to do so. You won't notice a...

A patient asked

Currently on TRT for about 8 years, doctor does not want to put me on HCG long tearm. I am only 37 and want to recover testicular function. Any studie...

AlphaMD's answer

There are not really long term studies on HCG that you could present, no, as that is still considered off-label technically. However, anecdotally, man...

A patient asked

What do you think about combining enclomiphene with a peptide to increase IFG1 to counteract enclomiphenes side effect of lowering IFG1?

AlphaMD's answer

Logically that makes sense and we get it, however there are not long term studies on this exactly. If you're cool with that you could be the test subj...

A patient asked

What you are doing is awesome guys! I would highly appreciate your input on my case. I have been working out in the gym/calisthenics/swimming/jogging...

AlphaMD's answer

To answer your questions in order:

A patient asked

What do you think of combining enclomiphene citrate with HCG as a way to boost test?

AlphaMD's answer

We would think that it would boost your Testosterone, but to keep in mind that these things improve your natural production. They are more effective t...

A patient asked

I'm in a bind right now with my situation. I've been on trt for 11 months, 150mg a week split into 3 shots. I also take hcg with every injection, 50...

AlphaMD's answer

While not knowing everything exactly and not wanting to step on anyone's toes, we'd suggest consulting with a fertility specialist rather than just a ...

A patient asked

While on a standard trt protocol (200 weekly) + hcg, at what testosterone level can one maintain fertility?

AlphaMD's answer

We do not necessarily agree with 200mg weekly being a "standard" dose. It is actually the highest use case dose that the DEA considers normal treatmen...

A patient asked

Why does institutional endocrinology insist on horribly outdated treatment protocols, when modern evidence says they're wrong? eg: I asked my nearly ...

AlphaMD's answer
A patient asked

How many patients have vision problems with clomid?

AlphaMD's answer

Between 1.5-3% of patients will experience vision problems with clomiphene. The higher the dose, the higher the likelihood. Most cases are reversible,...

A patient asked

I am wanting to switch my from clinic they absolutely refuse to stop infusing my TRT with anastrozole , what do you guys usually include in a protocol...

AlphaMD's answer

I'm guessing that the pharmacy that they use only sells their Testosterone Cypionate with that mixed in, or that they don't care to take things on a c...

A patient asked

Why is HCG impossible to get in certain states. We can’t get it in Arkansas. They don’t or won’t compound the medicine. Do y’all prescribe HCG or what...

AlphaMD's answer

The rules regarding

A patient asked

Why can’t you stay on HCG long term?

AlphaMD's answer

It is generally more of a concern about cost more than anything for the average American. When taking HCG with Testosterone, it is not adding much in ...

A patient asked

Are there any studies about TRT affecting sperm quality? I know about motility and sperm count. I mean specifically like denaturing of the sperm quali...

AlphaMD's answer

Testosterone does not cause birth defects. Remember what you are injecting is the same substance that has been coursing through your body every single...

A patient asked

Hi there, I have chronically low T , but not quite low enough that my doctors will prescribe it for me (hovers around 225-290 ng/dl) . I’m also trying...

AlphaMD's answer

For fertility purposes, clomiphene and enclomiphene are your best bets. They are the first line treatment used by fertility doctors to increase sperm ...

A patient asked

How much would 150mg of testosterone cypionate, 1000iu’s of HCG weekly be?

AlphaMD's answer

150mg of Testosterone Cypionate would be within our standard ranges and covered by our basic $129. For the HCG it would come down to the intended leng...

A patient asked

Do you guys prescribe HCG and can you telemed in Nevada? And what pharmacy do you guys use for compounding?

AlphaMD's answer

Yes, we can prescribe HCG & we are able to do telemedicine in Nevada. We use a handful of compounding pharmacies which have better prices on different...

A patient asked

I'm thinking about getting on TRT to boost my energy, libido, and mental performance. I would like to maintain my fertility too. What do you think abo...

AlphaMD's answer

Hey there, we had a few people review this since you were pretty clear.

A patient asked

Why is HCG impossible to get in certain states. We can’t get it in Arkansas. They don’t or won’t compound the medicine. Do y’all prescribe HCG or what...

AlphaMD's answer

Our compounding pharmacies are large continental US based rather than smaller and locally based. The reason your local ones probably aren't is because...

A patient asked

I’m in California. I’m already on with Royal. If I switched to you guys what would the cost be? Could you also get me on HCG and T?

AlphaMD's answer

There's no extra cost from switching TRT providers, we do accept current treatment plans but would still want to talk about how you're feeling on it.

A patient asked

Thoughts on use of enclomiphene as opposed to TRT?

AlphaMD's answer

The best case & results we've seen for it's use has been for men who have higher base Testosterone levels, aka relative hypogonadism TRT candidates. S...

A patient asked

I am currently self administering TRT 125mg PW Sustanon to be precise (35yo Male, no known medical conditions or physical health issues besides MH & L...

AlphaMD's answer

There is very little issue adding HCG full time to a TRT regimen, though you want to be reasonable and only use 500-1000 units a week. Closer to 1500 ...

A patient asked

My LH is zero. Will HCG fix that?

AlphaMD's answer
A patient asked

Other than fertility issues, are there any other concerns that a 26 year old man should have before starting trt? (Before starting I have taken 2 test...

AlphaMD's answer

In general, *current* fertility & hair loss are our main concerns for otherwise healthy young men.

A patient asked

I am currently on a protocol that is HCG based "monotherapy" it has been working great it seems, especially on bloodwork, but I wonder if I'm feeling ...

AlphaMD's answer

Clomid & HCG are fine together, they come at the problem from different avenues to try and accomplish the same thing.

A patient asked

Hi. 54 YO man. T was 170. Been on .75 Xyosted for 2 months. Now T is 420 and feeling good. But, the Testicular atrophy is killing me. Right Testicle k...

AlphaMD's answer
A patient asked

Makes sense. Apomorphine sounds promising on account of not requiring an injection, so I'll probably inquire about that first when I visit a doctor. H...

AlphaMD's answer

Apomorphine effects typically kick in 20min after the sublingual dose. Its effects typically last several hours..hCG should typically be dosed no less...

A patient asked

If a person would take HCGs the preserve fertility, how many injections can he expect to do weekly on a combo of TRT and HCGs Also, regarding libido,...

AlphaMD's answer

Someone looking to maintain fertility by using hCG while on TRT would typically dose at a minimum of 500 IUs/wk, with improving sperm levels with incr...

A patient asked

The longer you are on TRT, the harder it is to bounce back from, should you decide to go off, correct?

AlphaMD's answer

Yes and no. If you were to only take it for a few months, then recovery would be expected to be rapid, typically within a few months. The longest it h...

A patient asked

I'm all over the second, non medical advice. I have labs to test my ferritin & iron levels next week. If they look good I'm going to a different bloo...

AlphaMD's answer

Good planning with the lab tests, most donation companies don't talk to one another at all.I would be annoyed as well. It's really interesting the spe...

A patient asked

I was wondering if I could ask about my labs. Current 46 years old. Started feeling symptoms that could be associated with low t. I was also overweigh...

AlphaMD's answer

First, awesome job losing the weight and making lifestyle changes.

A patient asked

On daily cypionate and HCG but estrogen is high. Tried examestane and anastrazole which brings down to normal levels but I feel hollow sometimes and a...

AlphaMD's answer

It sounds like the goal is to maintain treatment and remove the need for AIs. With that in mind, you could consider reducing your HCG dose unless you'...

A patient asked

Would it make sense to be on 25mg of enclomiphene twice a week while on 140mg a week of test cyp to help preserve fertility? I was prescribed this and...

AlphaMD's answer

While you can, we would suggest to not if you're interested in the fitness aspects of TRT (which most men are).

A patient asked

I'm currently taking 60mgs test cyp, 500iu HCG and 25mcg anastozole twice a week. I'm new to HCG and strictly taking it for the neurological benefits ...

AlphaMD's answer

In general yes, though HCG is relatively safe for long term personal health (though a bit harmful to long term monetary costs depending how you get it...

A patient asked

Hey! I have elevated e2 of 70, total test of 400 maximum, lh 1.9, fsh 3.2 I feel testicle ache, shrinkage, and low T symptoms going on 2 years. Any ...

AlphaMD's answer

HCG monotherapy will still increase Estrogen compared to normal. You would probably be primary or secondary, yes. It may be work taking an AI, the onl...

A patient asked

What can cause severe anxiety and palpitations (especially at night) on trt and Hcg?

AlphaMD's answer

Well, TRT is not typically known to cause anxiety, though elevated estradiol levels can, so you should look into that. hCG is more likely to aromatiz...

A patient asked

How do you recommend coming off TRT if you have been on for many years?

AlphaMD's answer

A combination of Clomid/Enclomiphene & HCG is usually ideal. It would be fine to start those up while still on TRT for a few weeks if it's all planned...

A patient asked

I was on testosterone but quit a couple weeks back and now take HCG and Enclomiphene to try to get fertility back. Do you offer anything else that wou...

AlphaMD's answer

HCG & Clomid/Enclomiphene would be the same course of action that we would take for someone trying to cycle off of Testosterone to have a child. Thoug...

A patient asked

Hearing more about demesterol levels and enclomiphene as being a long term cardiovascular risk factor. Have u looked into that at all?

AlphaMD's answer

Desmesterol is the pre-cursor to cholesterol. Enclomiphene blocks the conversion of desmesterol into cholesterol by inhibiting the enzyme 24-dehydroch...

A patient asked

Sorry, but there's no such thing as a great dose. Take me, for example. Off 120mg my trough is 1344ng/dl. At 175mg, I was off the charts. My point is ...

AlphaMD's answer

I agree that everyone is different and that there will always be outliers, good stuff to share.

A patient asked

I’ve been on TRT for 6 months (160 mg weekly). Added HCG (1,500 weekly) 3 months ago. Balls though got firmer but still have not recovered to the pre-...

AlphaMD's answer

160mg a week is a great dose for Testosterone. For HCG 1500 units a week is what we would use for someone trying to actively conceive a child.A good ...

A patient asked

Don’t think I've got super low T but never felt like ive got good range of T either. Question is, can i do one cyxle and come off and see effects if i...

AlphaMD's answer

We would advocate to go through a traditional TRT practice so they can help guide the needs:dose and talk about it based on your symptoms. That said, ...

A patient asked

How does one start taking HCG with TRT? I want to try testosterone only initially and see how my body responds to it, then when I think I'm maintainin...

AlphaMD's answer

You would not need to adjust your Testosterone dose when adding HCG generally. HCG/Clomid increase your natural production. On Testosterone your natur...

A patient asked

Looking into stopping TRT for a while and starting enclomiphene (for fertility). I've read that clomiphene can get your test numbers into the referenc...

AlphaMD's answer

The reason it doesn't feel as good as normal TRT is that Clomid/Enclomiphene suppress IGF-1, which is what builds/maintains muscle & provides many of ...

A patient asked

I’m hoping to start TRT next month. Been dealing with terrible symptoms the last five years, got blood work done that showed low free and total T. I...

AlphaMD's answer

Yes sir, many men do. You could probably start on a mild dose of 500-1000 units weekly until you're actively trying and then kick it up to 1500 units ...

A patient asked

I've been noticing a lot of fatigue and brain fog the day before I take my Testosterone Cypionate. Is this just in my head since the half-life for Tes...

AlphaMD's answer

It is realistically closer to 4 days, and if you can tell a difference the day before your normal shot it would be perfectly fine to change to three t...

A patient asked

I know this isn’t TRT related but I’m a 20 year old male(344 ng/dl first test done at 8:30, and 311 ng/dl done at 9 am, 2 different dates) overall hea...

AlphaMD's answer

Clomid is a form of TRT the way we think of it, no worries.

A patient asked

Is there any information about using hcg with trt that contains benefits outside of fertility and ball size? I’m old and done with kids and don’t care...

AlphaMD's answer

There can be some. Some men have reported having better Estrogen levels or having it help with libido while on TRT.

A patient asked

Thoughts on using HCG + Enclomiphene in lieu of TRT for younger men with low testosterone worried about fertility?

AlphaMD's answer

They are fine ways to improve your Testosterone level, though each has some drawbacks.

A patient asked

What requirements do you require to get started with semaglutide, tirzepatiode or any of the following that you mentioned above ?

AlphaMD's answer

GLP-1s are less of a controlled medication that Testosterone & TRT is, which means the guidelines for use when not working with insurance justificatio...

A patient asked

For context, I'm a 35 year old male. I have had two blood test. The first of which stated: Finger prick blood test Total testosterone - 17.100 Free ...

AlphaMD's answer

Our opinion would be to rethink the goal & metrics a bit. For TRT & why you've been denied care, many institutions like insurance companies or very ol...

A patient asked

How are you guys feeling with using Enclomiphine as a means to preserve testicular function vs HCG while on testosterone? Have you tried combining the...

AlphaMD's answer

So, we are a bit more conservative in that we don't feel like the science has proven any benefit for use of a SERM and TRT concurrently.

A patient asked

My wife and I I look to try for our third child next year, first post TRT, I wanted to get your thoughts on what i should be researching, asking my pr...

AlphaMD's answer

So, to keep it simple, TRT is male birth control. While some men still can produce sperm while on TRT, you should never assume you are one of them. A...

A patient asked

When these neurosteroids bottom out, would that cause adhd medications to stop working? Would introducing HCG be a better option than supplementing wi...

AlphaMD's answer

Yes, when these neurosteroids are depleted, it would make focus and attention worse. This would typically mean that any treatments for attention would...

A patient asked

Any downside to micro dosing HCG? I take 60 units per week, 17 units EOD. I have heard it is not as effective at low doses. True? Would I be better of...

AlphaMD's answer

I wouldn't say there's a downside to micro dosing vs more spread out injections on paper. The trouble is that when you're working with those very very...

A patient asked

I see many people on this sub post with bloodwork confirming that while on TRT (test only, no HCG) all health markers look great/within range and they...

AlphaMD's answer
A patient asked

Thoughts on Enclomiphine Vs HCG alongside testosterone for the sole purpose of preventing testicular atrophy? I just started EOD 12.5mg Enclomiphine ...

AlphaMD's answer

There are no studies on using enclomiphene and TRT together, but it is becoming a more common practice. Logically, it keeps your FSH and LH production...

A patient asked

What’s your favorite hair protective method for someone who is prone to baldness? Also subq vs IM? The age old question. I started with HCG mono and ...

AlphaMD's answer

When it comes to TRT, Testosterone at a therapeutic dose (getting you to where you should be) typically doesn't cause additional* hair loss. However i...

A patient asked

Is HCG the recommended product to return testicular size when on a TRT regimen?

AlphaMD's answer

Generally yes. There are a few other things that can help, but HCG is going to be the most direct & effective.

A patient asked

I am considering trt to improve my gym performance and physique. I'm wondering if I decide to stop trt one day, how long will it take for my own body ...

AlphaMD's answer

Many more recent studies show that 6 months to 1 year for production levels to return to normal completely unassisted.

A patient asked

Why is hCG so expensive?

AlphaMD's answer

A good few years ago they changed the regulations regarding its manufacture, making it a much harder process on the production side of things. This c...

A patient asked

What’s your recommended dose for hcg weekly to maintain fertility and testicular size? And it hcg increases e2 too much is it fine to take an AI long ...

AlphaMD's answer

Anywhere from 250-1000 units weekly will have a good effect for cosmetic size & can be considered a maintenance dose. Many men opt for 500 units weekl...

A patient asked

What could I expect cost wise to start on TRT and include HCG for fertility purposes? Considering it and no clue what to expect for cost. I know there...

AlphaMD's answer

Almost all clinics are going to cost around an average of $130-150 a month, despite whatever they say, for baseline TRT (no HCG). There are some like ...

A patient asked

My doctor is only testing free testosterone for medically prescribed TRT at my appointments. What other levels and things should I ask him to check? ...

AlphaMD's answer

Truthfully if you're only on a moderate dose of TRT, it is providing the benefits you're looking for, and you have no side effects - Basic Testosteron...

A patient asked

I am completely confused about TRT. I see people here talking about HCG, AI, different gauge needles, amounts, different types of Testosterone. Can y...

AlphaMD's answer

Yeah! No worries. A lot of men are in the same boat. Happy to clear up what I can here too.

A patient asked

Im dealing with : Shortness of breath, severe cognitive issues (memory, verbal fluency, cant remember simple words during conversation) Water retentio...

AlphaMD's answer

Well, the shortness of breath is an indication that your symptoms may not be related to your hormones. You have described symptoms that could be relat...

A patient asked

What dose of hcg would you recommend when starting TRT?

AlphaMD's answer

The dose would depend on the purpose & a bit on financial reach.

A patient asked

I’ve put a post on here recently. I am waiting for more blood test results but previously I had high SHBG, high total T, high e2, low normal free T. I...

AlphaMD's answer

With high E2 that is probably true, for men with low Estrogen they can certainly bottom out their Estrogen even with a basic AI dose.

A patient asked

Do you recommend HCG along with TRT? Not for fertility but for other benefits? Like keeping testicle size normal?

AlphaMD's answer

We would be neutral on HCG with TRT if not for fertility.

A patient asked

Can HCG cause itching/tingling nips and enlarged breasts? I was doing fine until (under doctors orders) I injected 500iu HCG. Woke up this morning wit...

AlphaMD's answer
A patient asked

How often do you see HCG doing nothing to preserve fertility? I had to completely quit all TRT for 6+ months to regain my fertility. I was on 250iu t...

AlphaMD's answer

Very rarely.

A patient asked

Would you treat a 23 year old male? Also how much are your clinic fees? Ie; start up fees, medication costs, any recurring fees. Thanks!

AlphaMD's answer

Yes, we would and have - If they are suffering from low T symptoms & we can determine there is no underlying condition during a consultation.

A patient asked

Do you offer hcg?

AlphaMD's answer

Yes, we do. It is an ancillary medication for TRT which comes with an increased cost because it is quite expensive. We should probably list that more ...

A patient asked

Is there any point in taking hcg and clomid at the same time? Would hcg cancel clomid's effect out? Like clomid trying to kick pituitary to function w...

AlphaMD's answer

There are no studies on this practice of using both at the same time, but logically speaking, using them together doesn’t really make sense. HCG attac...

A patient asked

Does timing matter for HCG injections? Husband is adding hCG (3x/week MWF) to usual TRT (2x/week Sun/Thurs) to regain fertility, and didn’t know if AM...

AlphaMD's answer

Generally no. With hCG it is less direct than with TRT, as it's not the medication itself causing a level to change but the downstream effects which p...

A patient asked

Hello, I had low T but normal LH and FSH levels last year. Sperm count and quality was also good. I started HCG monotherapy (1500 IU twice a week) aro...

AlphaMD's answer

So, primary hypogonadism is typically diagnosed when LH levels are normal are high, and testosterone level is low. Basically, LH is the gas pedal tel...

A patient asked

I need to take hCG because, simply put, my testicular pain disappears. So, I undergo treatment just to maintain testicular health and size. In this c...

AlphaMD's answer

If it is simply for this reason and nothing else, then it would make sense that the lowest possible dose while still providing the benefit you are loo...

A patient asked

What benefits do you typically see from monotherapy with HCG?

AlphaMD's answer

The removal of low Testosterone symptoms would be number one on the list. Essentially, effectiveness goes somewhat in this order: Injection T > Topica...

A patient asked

If you are someone who has no fertility concerns (family planning is done) is there any benefit to taking hCG alongside TRT. My clinic has me on test...

AlphaMD's answer

It would mostly be used for testicle size & fertility.

A patient asked

I’ve read you should take hcg for 20 days then stop for a while and others say take it as long as you want. What’s a good protocol. I’ve been taking m...

AlphaMD's answer

The reasoning is that you do become a bit desensitized to it over time, which can require a higher dose. However outside of that there's not many othe...

A patient asked

I switched from my primary doctor to a TRT clinic a month ago in order to get HCG along with my test, and 2 weeks after my first hCG dose I am told I ...

AlphaMD's answer

Yes, we do!

A patient asked

Thoughts on Kisspeptin and how it compares to hCG?

AlphaMD's answer

Kisspeptin works in a different pathway. Kisspeptin is produced in the hypothalamus and acts upon KISS1 and GPR54 receptors to stimulate the release o...

A patient asked

Would you say that TRT with hCG is a much better option for someone that wants to maintain fertility as opposed to Enclomiphene mono therapy? I was co...

AlphaMD's answer

We would say that, yes. In general although Enclomiphene appears to have less side effects than Clomid, it has not been around as long as these other ...

A patient asked

Are there any viable alternatives to hCG when trying to maintain fertility on testosterone? If not, are there any being studied or developed? I've be...

AlphaMD's answer

There are some, like Enclomiphene or Clomid, but they are not as safe & effective as hCG is for the same purpose. That said, for many men like yoursel...

A patient asked

Question regarding HCG and HTN: I had a weird experience on 200units of HCG. I was prescribed 500 units three times a week but did a test dose of 200u...

AlphaMD's answer

First of all this sounds very scary and I am glad to hear that you have no long-term affect from this incident. I'm also glad to hear that you were cl...

A patient asked

Is there cream or gel for hCG plus TRT?

AlphaMD's answer

No sadly, for hCG you would need to use an injectable given what is available on the market right now.

A patient asked

What happens if my provider gives me hCG for 6 months with the same vial when it says one month is the max on the bottle ? Is it still good ?

AlphaMD's answer

For hCG & the listed 60 days (or 30 days depending on the state that you are in); The discard date (sometimes labeled as expiration date) is not the s...

A patient asked

I used to have cumshots that would make a pornstar jealous. I know hCG is mainly for fertility, will it also help me with the cumshot?

AlphaMD's answer

Yes & no. Only a small portion of ejaculation comes from the testicles, which is why it's not a major concern/complaint when someone has a vasectomy....

A patient asked

I've been wondering about something about hCG in regards to RBC, hematocrit, and hemoglobin. It's well-known that exogenous testosterone use will rais...

AlphaMD's answer

TRT and hCG can/will cause some elevation of hematocrit and/or hemaglobin. Changing doses doesn't usually get H&H into better ranges. The best method ...

A patient asked

I started HCG 1200 IU weekly at the same time as 100 mg test, with no AI. If my bloods come back normal but with high e2, would the first course of a...

AlphaMD's answer

It would depend on a few things. First, how you're feeling on the two medications & what your Testosterone comes back as. If you are feeling great wit...

A patient asked

If I accidentally left reconstituted hCG out of the fridge. How long is too long and I should be worried if at all?

AlphaMD's answer

Generally this is fine depending on how long you plan to use it for. Some men don't even refrigerate their hCG because their dose is high enough that ...

A patient asked

Do you believe it’s likely to have kids while onTRT if using hCG regularly? I’ve been in TRT for a 4+ years but have only been using hCG for the last...

AlphaMD's answer

HCG can keep your sperm count high enough for conception. You can get a sperm count done, but generally you should have high enough to conceive.

A patient asked

Is there any disadvantage to HCG monotherapy as opposed to TRT?

AlphaMD's answer
A patient asked

Assuming cost isn’t an issue, what’s the best dose of HCG as a supplement to TRT? I’ve seen as low as 500iu weekly and as high as a few thousand. What...

AlphaMD's answer

"Best" dose is always individual, but here is a quote from a frequently cited study that will help explain things:

A patient asked

I’m on test 100 mg per week pinned twice a week. I recently added 500iu hcg split twice weekly. Almost immediately I got acne on my chest back and arm...

AlphaMD's answer

It sounds like you were right at your sweet spot for Testosterone levels where your body didn't see it as an issue & aromatase into extra estrogen. Ad...

A patient asked

I was just prescribed HcG from my endocrinologist. I’ve been on Clomid for a year and it has made me feel awful. I’m a different person on it. What ca...

AlphaMD's answer

In general there are a lot of side effects with Clomid compared to HCG, especially if we're talking monotherapy without additional Testosterone. Assum...

A patient asked

I'm currently taking half a ML a week of pregnyl on top of half a ML of test cypionate, with that dosage a bottle would last me 20 weeks. The shelf li...

AlphaMD's answer

So, the "shelf-life" is how long an FDA medication can "gurantee" sterility after puncture. The actual medication in the vial remains viable for up to...

A patient asked

Many people are talking about using hcg instead of clomid, but hgc is simply an analogue of LH. when it comes to fertility explicitly you need both go...

AlphaMD's answer

You are right in that Clomid provides better fertility than hCG because it also increases FSH, which we now know matters less for sperm count, and mor...

A patient asked

Endo has me on clomid and trt. Would they switch me to hcg instead? Is it better to use than clomid?

AlphaMD's answer

The SERM (clomiphene or enclomiphene) and TRT combo is still experimental and not proven science. The hCG plus TRT is proven and the gold standard for...

A patient asked

Why has it been so hard to find a pharmacy that can fill compounded hCG?

AlphaMD's answer

Due to new FDA regulations, access to compounded hCG is now extremely restricted and may at some point stop altogether. This means an already low supp...

A patient asked

Is there a shortage of hCG in the US?

AlphaMD's answer

Yes. There has been less hCG available in general terms for all pharmacy distributors across the board.

A patient asked

Is there any reason to use Testosterone Cypionate and Enclomiphene concurrently?

AlphaMD's answer

There are two negative feedback loops on LH release, estrogen and testosterone.

A patient asked

How important is it to start HCG with TRT if conceiving isn't in the plans for several years down the line? Once on TRT, how soon should hcg be starte...

AlphaMD's answer

All studies on concurrent use of hCG on TRT were done as a recovery study, not a preservation study. What that means is, all the data we have about hC...

A patient asked

I have been in enclomiphene for a year, but my test has been going down, and I just haven't been feeling as great as I did overall after starting the ...

AlphaMD's answer

Based on how you've responded, and how adding that has gone - We'd suggest swapping to injectable TRT & HCG for fertility instead. The main issue with...

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